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Inflammatory Bowel Disease, 2nd edition presents updated information about inflammatory bowel disease in health-care workers. The theoretical content is based on controlled and randomized clinical studies in the meta-analyzes, conducted appropriately and especially in global consensus and led by international experts. As such, the reader has access the important topics required to understand the ulcerative colitis and Crohn's disease.The editors and chapter authors, all established names within gastroenterology and coloproctology, and having extensive experience in assisting patients with inflammatory bowel disease, provide a concise book with quick and objective reference texts that complement the knowledge of students, doctors, nurses, nutritionists and psychologists of daily clinical practice.
This book is a practical and comprehensive guide to the diagnosis and treatment of human papilloma virus (HPV)-related diseases from a urological perspective. It reviews new diagnostic methods for virus detection and typing, management of penile and urethral lesions, new treatment modalities including an overview of the use of lasers, the link between HPV and cancer, and new prevention methods with an update on HPV vaccines.
The treatment of inflammatory bowel disease (IBD) has posed a major challenge since its appearance. Biomedical researchers, physicians, gastroenterologists, and surgeons have struggled to improve the quality of life of their patients and have sought, above all else, to keep the disease under remission for as long as possible. Blockers for tumoral necrosis factor alpha (TNF-alpha) were the first biological drugs to be discovered and for this reason they played a crucial role in the subsequent evolution of IBD treatment. The aim of this book is to provide an overview of such drugs and the latest developments in IBD immunopathology. Our contributors discuss the main indications, efficacy, and possible side effects of the different types of drugs available today for IBD treatment.
How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able not only to mechanically support cells, but also to release signals biologically relevant for governing stem cell fate. In addition, increasing evidence suggests that abnormal interaction of stem cells with their niche is responsible for altered cell function leading to malignant transformation. This ...
With the increased incidence of HPV-related genital diseases, including premalignant and malignant penile lesions, urologists and practitioners in general face numerous difficult challenges when attempting to diagnose genital lesions correctly. Despite the importance of genital lesions in the male, there are few books on the subject in the English medical literature. Male Genital Lesions will serve as an invaluable aid to the differential diagnosis of sexually transmitted infections, benign dermatological genital lesions, and premalignant and malignant genital disorders. More than 700 high-definition full-color figures of common disease presentations are included, with legends describing real clinical cases. The illustrations are supported by a concise, up-to-date text that describes etiology, pathology, clinical manifestations, laboratory tests, and treatment options for the individual diseases.
This is the first comprehensive book exclusively dedicated to anorectal physiology and the importance of diagnostic tools in guiding the evaluation and treatment of anorectal dysfunction. Functional disorders, and specifically fecal incontinence and evacuatory disorders, are prevalent in the general population, affecting up to 20% of individuals. As many of these conditions have extremely complex mechanisms, a thorough understanding of anorectal physiology is a crucial element in the surgeon’s “arsenal" to ensure accurate evaluation and to inform treatment. At this time, there is no other title that specifically addresses all aspects of anorectal physiology, as well as anorectal and pelv...
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