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Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science
This book provides an up-to-date overview of key areas of ageing research and bridges the gap between the subcellular events and the reality of ageing as seen in clinical practice. To this end, the reader learns about the historical development and progression of clinical ageing research. All chapters address the biochemistry or cell biology of various ageing events (to the extent that the data are available) and work their way to the clinical understanding we have of ageing. The focus of this volume is on how dietary restriction, virus infection and chronic inflammation affect the ageing process. Additionally, this book discusses how phosphate metabolism and metabolic dysfunction contribute...
Extending healthy ageing across the life course
This was the second virtual meeting to initiate WHO’s new area of work on connecting healthy development and healthy ageing throughout the life course, following the first in June 2022. The meeting put into practice the approach to collaboration that will draw on everyone’s expertise and interest. Over 120 participants joined from all six WHO regions. Participants included persons from life course centres, experts in individual life stages – including children, adolescents, adults and older adults – members of the Consortium on Metrics and Evidence for Healthy Ageing (CMEHA) – including academics, civil society representatives and policy-makers – as well as staff from WHO and other international agencies.
Aging Research - Methodological Issues
This is the second edition of a well received book that reviews classical epidemiological and clinical research designs, with a specific focus on aging. Chapters cover basic topics like the scientific method, ethics, and the consequences of certain exclusion criteria. The work also includes a look at clinical concepts like multimorbidity, frailty and functionality. New material includes chapters such as geroscience, health systems research, big data and data mining, financing and future of aging research. The authors reveal the issues and challenges for researchers of age and aging, and also consider, from basic to clinical, and from clinical to public policies of social and health care. The...
WHO consortium on metrics and evidence for healthy ageing
The 2020 annual meeting of the WHO Consortium on Metrics and Evidence for Healthy Ageing was the fourth gathering of an international group of experts from all WHO regions, including policy-makers, civil society organizers and researchers, drawn from the full breadth of the field of ageing to progress the work agreed by Member States under the 2016 WHO Global Strategy and Action Plan on Ageing (GSAP) and the UN Decade of Healthy Ageing (2021-2030). This meeting report summarizes the discussions on the contributions of CMEHA members to the Decade of Healthy Ageing: Baseline Report (launched 17 December 2020), and next steps in view of the strengths, gaps and opportunities identified. It also outlines the next steps for implementing the Decade of Healthy Ageing in line with metrics and evidence, and derivative products related to the Baseline Report.
Social Isolation and Loneliness in Older Adults
Social isolation and loneliness are serious yet underappreciated public health risks that affect a significant portion of the older adult population. Approximately one-quarter of community-dwelling Americans aged 65 and older are considered to be socially isolated, and a significant proportion of adults in the United States report feeling lonely. People who are 50 years of age or older are more likely to experience many of the risk factors that can cause or exacerbate social isolation or loneliness, such as living alone, the loss of family or friends, chronic illness, and sensory impairments. Over a life course, social isolation and loneliness may be episodic or chronic, depending upon an in...
Handbook of Anthropometry
Although its underlying concept is a relatively simple one—the measurement of the human body and its parts—anthropometry employs a myriad of methods and instruments, and is useful for a variety of purposes, from understanding the impact of disease on individuals to tracking changes in populations over time. The first interdisciplinary reference on the subject, the Handbook of Anthropometry brings this wide-ranging field together: basic theory and highly specialized topics in normal and abnormal anthropometry in terms of health, disease prevention, and intervention. Over 140 self-contained chapters cover up-to-date indices, the latest studies on computerized methods, shape-capturing syste...
Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.B)
Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.
Strengthening the Scientific Foundation for Policymaking to Meet the Challenges of Aging in Latin America and the Caribbean
Recent demographic trends in the Latin American and Caribbean (LAC) region will shape the growth and age composition of its populations for decades to come. The rapid mortality decline that began during the 1950s, and the more recent and even sharper reduction in fertility, will produce unusually high rates of growth of the older population, a large change in overall population age composition, and significant increases in the ratio of older to younger population. According to the 2013 United Nations projections, the number of people aged 60 and over in LAC is expected to increase from 59 million in 2010 to 196 million in 2050, and the number of people aged 80 and over will increase from 8.6...
