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The first woman in America to own and operate a circus, Agnes Lake spent thirty years under the Big Top before becoming the wife of Wild Bill Hickok—a mere five months before he was killed. Although books abound on the famous lawman, Agnes’s life has remained obscured by circus myth and legend. Linda A. Fisher and Carrie Bowers have written the first biography of this colorful but little-known circus performer. Agnes originally found fame as a slack-wire walker and horseback rider, and later as an animal trainer. Her circus career spanned more than four decades. Following the murder of her first husband, Bill Lake, she was the sole manager of the “Hippo-Olympiad and Mammoth Circus.” While taking her show to Abilene, she met town marshal Hickok and five years later she married him. After Hickok’s death, Agnes traveled with P. T. Barnum and Buffalo Bill Cody, and managed her daughter Emma Lake’s successful equestrian career. This account of a remarkable life cuts through fictions about Agnes’s life, including her own embellishments, to uncover her true story. Numerous illustrations, including rare photographs and circus memorabilia, bring Agnes’s world to life.
The role of dopamine in schizophrenia has been a significant area of research. The measurement of the major dopamine metabolite, homovanillic acid (HVA), in various body fluids, especially in blood plasma, is one of the primary methods to assess brain dopamine neuronal activity in schizophrenic patients. Written by leading researchers in the field, Plasma Homovanillic Acid in Schizophrenia provides the most comprehensive and current collection of information on plasma HVA levels to be found anywhere. It provides a concise synthesis and critique of current data as well as interesting proposals for future research. This book will be of great value to any serious student of the biology of schizophrenia and other psychiatric disorders involving abnormal levels of plasma HVA.
"Business during the Week was very dull. The great Plague of the Year Cholera is driving every Country [person] and Merchants from Surrounding Cities away. The City looks like a desert Compared to its usual animated appearance. Last week ending the 6th there were 78 deaths from it, altogether 173. This week ending yesterday 278 deaths 189 from Cholera. People parting for a day or so, bid farewell to each other. My Partners family are fortunately in the Country. I and Clemens sleep in the Same bed, in Case of a Sudden attack to be within groaning distance. . ." --Diary entry for Sunday, May 13th, 1849 Joseph J. Mersman was a liquor merchant, a German American immigrant who aspired--with succe...
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