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Neurogenesis and Neural Plasticity
This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.
Biologie des émotions
Que se passe-t-il dans notre cerveau quand nous avons peur ou que nous sommes en colère ? Pourquoi ressentons-nous des modifications corporelles (accélération du rythme cardiaque, sudation, etc.) lorsque nous sommes émus ? Pourquoi certains sont-ils plus méotifs que d'autres ? Ce manuel très didactique nous fait décourvrir les découvertes les récentes dans ce domaine de recherche en plein essor qu'est la psychobiologie. On y trouve une description générale des corrélats biologiques (cérébraux, génétiques, endocriniens) des émotions telles que la peur, la colère, le rire, etc. Conçu dans une perspective résolument intégrative et non réductionniste, l'ouvrage s'ouvre sur une partie plus générale dans laquelle l'auteur pose les bases de cette discipline (définition des émotions, différentes théories psychologiques, variations culturelles dans l'expression des émotions, grands débats, etc.) et passe en revue les différents systèmes biologiques impliqués. On trouvera ensuite exposé le substrat biologique de chaque émotion abordée par l'auteur (peur, dégoût, douleur, plaisir, rire, etc.).
Psychiatric Vulnerability, Mood, and Anxiety Disorders
This volume looks at classic and novel methods currently used by researchers to understand mood and anxiety disorders and foster precision medicine. Chapters in this book cover topics such as how the sucrose preference succeeds or fails as a measurement of anhedonia; fear conditioning in laboratory rodents; animal models for mania; rodent models for studying the impact of variation in early life mother-infant interactions on mood and anxiety; and prediction of susceptibility/resilience toward animal models of PTSD. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, accommodating the novel views on how the neurobiology of psychiatric disorders should be reconceptualized, Psychiatric Vulnerability, Mood, and Anxiety Disorders: Tests and Models in Mice and Rats is a valuable resource for all researchers interested in learning more about this important and developing field.
The Rise and Fall of Animal Experimentation
Every year, hundreds of millions of animals are used in the service of biomedical research, despite the risk of extreme cruelty to these animal subjects. The expansion of the pharmaceutical industry and university research funding rapidly normalized its practice. What exactly are these experiments supposed to achieve from the scientific point of view and how effective are they? Working scientists answer these questions by saying that their research is absolutely necessary if we are to develop new therapies for human diseases. But is this really the case? Written by a scientist with over 40 years of laboratory experience, The Rise and Fall of Animal Experimentation critically examines this as...
Psychology
This book represents a selection of chapters that address several topics from the broad domains of psychology: alcoholism, clinical interventions, treatment of depression, personality psychology, qualitative research methods in psychology, and social psychology. As such we have interesting blend of studies from experts from a diverse array of psychology fields. The selected chapters will take the reader on an exciting journey in the domains of psychology. We are sure the content will appeal to a great audience.
Depression: From Psychopathology to Pharmacotherapy
Despite the availability of antidepressants for over 40 years, a substantial proportion of depressed patients do not respond adequately to treatment. Failure to respond effectively to treatment contributes to physical ill-health and psychiatric morbidity, often resulting in premature death of the depressed patient. The purpose of this volume is to consider the possible reasons for the limitations of the currently available antidepressants, to examine the advances in our understanding of the psychopathology of depression and how such knowledge may assist in the discovery of new methods of treatment. Leading international experts in this field discuss the possible underlying reasons for depression and limitations of current antidepressants. Opportunities for novel therapeutic approaches to dysfunctional circadian rhythms and mood disorders as well as current status and future perspectives for optimizing antidepressant management of depression are reviewed. This publication illustrates the breadth of the latest research and is valuable reading for psychiatrists, neuroscientists and pharmacologists.
