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University Bulletin
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Innate Immune Regulation and Cancer Immunotherapy
Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: inhibiting or promoting tumor growth and progression. Although regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against self- or non self-antigens, thus playing critical roles in preventing autoimmune diseases, they might inhibit antitumor immunity and promote tumor growth. Recent studies demonstrate that elevated proportions of Treg cells are present in various types of cancers and suppress antitumor immunity. Furthermore, tumor-specific Treg cells can inhibit immune responses only when they are exposed to antigens presented by tumor cells. Therefore, Treg cells at tumor sites have detrimental effects on immunotherapy directed to cancer.
Microscale Energy Transfer
This text explores the field of microscale heat transfer in mechanical engineering. Experts from a wide range of science and engineering disciplines present topics that are built from simple macroscopic concepts and gradually lead into microscopic concepts. The book begins with an introductory chapter which discusses the history and the future directions of microscale heat transfer. It is then divided into two sections: the Fundamentals and the Applications.
MEMS Mirrors
This book is a printed edition of the Special Issue "MEMS Mirrors" that was published in Micromachines
Multiphase Flow And Heat Transfer
These essays present the latest international research results in the field of multiphase flow and heat transfer. They are based on papers presented at the "Second International Symposium on Multiphase Flow and Heat Transfer" conducted in China in 1989.
