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Integrative Pharmacology-based Research on Traditional Medicine: Methodologies, Medical and Pharmacological Applications
ntegrative Pharmacology can be used to determine the multi-pharmacological effects of traditional medicines such as traditional Chinese medicine (TCM), Kampo, Sa-sang, Ayurveda, etc.). Through qualitative and quantitative pharmacokinetic-pharmacodynamic (PK-PD) correlations among multi-constituents and multi-targets, integrating chemical profiling, ADME/PK processes, molecular network calculation and resulting experimental validation, the use of Integrative Pharmacology has become widespread. The data has provided a novel paradigm to evaluate the druggability of bioactive ingredients of herbs or formulae, to decipher the pharmacological mechanisms of drug action and to screen potentially new indications for approved drugs and previously unidentified adverse events. On this basis, Integrative Pharmacology may offer an effective way to test the potential scientific basis for traditional medicines and to assess what roles of traditional medicine can and cannot play in pharmaceuticals.
Immunomodulatory Agents from Plants
The human immune system, despite having its own sophisticated defence mecha nisms, is inferior to bacteria and viruses with respect to adaptability. Furthermore, our immune system is increasingly exposed to detrimental effects, that is immuno suppressive environmental consequences, unhealthy living, and chronic illnesses. Excessive chemotherapy threatens our immune system even further. This situation demands compensatory prophylactic therapeutic regimes. One of these - specific immunostimulation - is more difficult to achieve than the immunosuppression cur rently used in transplantation surgery and the medical treatment of autoimmune dis eases. The earliest attempts to develop suitable medic...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Face Book
None
Common Chinese Materia Medica
This ninth volume describes 285 species of medicinal plants of 30 families, which are commonly used in Chinese medicine. The most important species are Alisma orientale of Alismaceae; Commelina communis of Commelinaceae; Eriocaulon buergerianum of Eriocaulaceae; Alpinia galanga, Alpinia hainanensis, Alpinia officinarum, Alpinia oxyphylla, Amomum compactum, Amomum kravanh, Amomum villosum, Amomum villosum var. xanthioides, Amomum longiligulare, Amomum tsao-ko, Costus speciosus, Curcuma aromatica, Curcuma kwangsiensis, Kaempferia galanga, Zingiber officinale of Zingiberaceae; Anemarrhena asphodeloides, Asparagus cochinchinensis, Disporum cantoniense, Fritillaria cirrhosa, Fritillaria delavayi,...
Representation Learning for Natural Language Processing
This book provides an overview of the recent advances in representation learning theory, algorithms, and applications for natural language processing (NLP), ranging from word embeddings to pre-trained language models. It is divided into four parts. Part I presents the representation learning techniques for multiple language entries, including words, sentences and documents, as well as pre-training techniques. Part II then introduces the related representation techniques to NLP, including graphs, cross-modal entries, and robustness. Part III then introduces the representation techniques for the knowledge that are closely related to NLP, including entity-based world knowledge, sememe-based lin...
