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Mitonuclear Ecology
This novel text provides a concise synthesis of how the interactions between mitochondrial and nuclear genes have played a major role in shaping the ecology and evolution of eukaryotes. The foundation for this new focus on mitonuclear interactions originated from research in biochemistry and cell biology laboratories, although the broader ecological and evolutionary implications have yet to be fully explored. The imperative for mitonuclear coadaptation is proposed to be a major selective force in the evolution of sexual reproduction and two mating types in eukaryotes, in the formation of species, in the evolution of ornaments and sexual selection, in the process of adaptation, and in the evolution of senescence. The book highlights the importance of mitonuclear coadaptation to the evolution of complex life and champions mitonuclear ecology as an important subdiscipline in ecology and evolution.
Vision and eye screening implementation handbook
The WHO Vision and eye screening implementation handbook (VESIH) offers a step-by-step guidance for conducting vision and eye screenings in community and primary care settings. The evidence-based interventions are drawn from the WHO Package of eye care interventions and developed with a focus on delivering screenings easily, safely, and effectively in low- and low–intermediate-resource settings. The early identification through screenings ensures timely treatments and management to avoid vision impairment in high-risk populations, including newborns, pre-school children, school children, and older adults. To further support country approaches, the VESIH incorporates a section on the advantages and disadvantages of diverse vision and eye screening approaches. Additionally, various pathways for refraction and spectacles service delivery are outlined, along with actionable recommendations aimed at enhancing refractive error services. The VESIH serves as a comprehensive guide for effective vision screenings in diverse settings, contributing to WHO SPECS 2030, in particular, to improve access to refractive services.
Hydrogenase: Structure, Function, Maturation, and Application
Molecular hydrogen (H2) is an important molecule in the metabolism of diverse microorganisms. It is used either as energy source or for the disposal of reducing equivalents depending on environmental conditions. Furthermore, H2 transmits energy between different species within microbial communities. The enzymes that split or evolve H2 are called hydrogenases and these metalloproteins can be divided into three phylogenetically unrelated classes distinguishable by the metal composition of their active sites, namely [Fe]-, [FeFe]-, and [NiFe]- hydrogenases. Following a century of hydrogenase research, it is now possible to isolate, handle, and investigate these fragile enzymes. There have been numerous advances in understanding the regulation, function, structures, and maturation of these enzymes, as well as their involvement in important processes such as microbial pathogenesis and biogeochemical cycling. The employment of hydrogenases and hydrogenase-based applications could also potentially facilitate the world’s transition to a future sustainable H2-based energy economy.
The IOS 5 Developer's Cookbook
Provides information on building iOS 5 applications for iPhone, iPad, and iPod Touch.
Growing up Lansdowne
Growing Up Lansdowne is a photo-illustrated account of the authors childhood and adolescence in the mid to late 1950s and eventful 1960s in Lansdowne, Pennsylvania, a conservative Philadelphia suburb. The book is composed of 171 diverse essays depicting growing-up years in Lansdowne. Eight sections titled Random Remembrances record dozens of additional recollections. Assorted photographs are included to accent the narrative. The book is part memoir, part social landscape, part local/national history, and part love story. The recollections reflect candor and vulnerability, and at times they are surprisingly personal. Essays present balanced portraits of family and community life and the general era without resorting to enhancement or exaggeration. By its very design, Growing Up Lansdowne compels readers to make personal comparisons with their own hometowns and upbringing. The text touches upon memorable historical events and sensitive social issues of the times, and their impact on adolescent transition to adulthood.
Cryo-Electron Microscopy in Structural Biology
Cryo-electron microscopy, in combination with tomography, has emerged as a new technology for visualizing molecular structures at a resolution beyond even 1 Å. Using this technology has revealed the native molecular details of viruses, membranes, enzymes, ribosomes, and cells. This comprehensive volume brings together authoritative overviews of these methods from structural and biological perspectives. It is a must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, structural biology, crystallography, and genomics. Key Features • Focuses on the applications of cryo-EM to structural biology • Documents the importance of cryo-EM/ET approaches in studying the structural determinants of cellular organelle and membrane protein biochemistry • Reviews the applications of high-resolution structures of viruses • Emphasizes structural insights of nuclear and gene machineries • Includes a section focused entirely on the applications of cryo-EM/ET in drug discovery and therapeutic development
From Burleigh to Boschink
From Burleigh to Boschink: A Community Called Stony Lake covers over a hundred years of human history, encompassing the Aboriginal Peoples, their presence and influence, early settlement and cottaging activity up to the present time. Family stories, local lore, boats and steamers, recreational opportunities, personalities and environmental concerns are all presented through the writings, the voices and the memories of those who were there and, in some cases, still are. Richly supported by rare photographs and other visuals of Stony Lake, this publication will bring delight to many.
Clare Through the Twentieth Century
Numerous histories have been written of the older colleges of Oxford and Cambridge. During the 20th century, Clare, founded in 1326, has two - Manfield Forbes' eccentric six century survey up to 1926, and Richard Eden's recent Clare College and the Founding of Clare Hall. However no previous attempt has been made by the College, or as far as is known by any Oxbridge college, to present a wide-ranging overview of college life and learning through the 20th century.
The Oxford Handbook of Video Game Music and Sound
Bringing together dozens of leading scholars from across the world to address topics from pinball to the latest in virtual reality, The Oxford Handbook of Video Game Music and Sound is the most comprehensive and multifaceted single-volume source in the rapidly expanding field of game audio research.
