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Frederick
Frederick has stood as the gateway to western Maryland since the 1740s, when German and English settlers moved into the area seeking fertile farmland. Site of the first official rebellious act of the American colonies, early Frederick Town shared the fortunes of the growing nation as proximity to the new capital in Washington and the port of Baltimore fed industry and culture here along the Monocacy River.
Star Spangled Security
Harold Brown served as U.S. secretary of defense when the Soviet Union posed an existential threat with superior conventional force capability and a daunting nuclear weapons arsenal. No one could have been better suited to deter the Soviets during that most dangerous period in the Cold War. A physicist, Brown had previously led Livermore Laboratory and its development of the Polaris missile warhead. By age 33 he was director of Defense Research and Engineering, and he later served as secretary of the U.S. Air Force early in the Vietnam War. In the Carter administration, Brown reinvigorated the NATO alliance, promoted AWACs, increased U.S. conventional force capabilities, and developed a new ...
Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
With Justice for All
Social history is only one kind of history. Still, it is exactly the type of history that disability demands to be told, especially due to the universality of the disability experience. Doris and Frieda Zames remind us that “handicapism” is the only “ism” we all will experience if we live long enough. Although disability will always arguably be about physical differences (of body, mind, intellect, personality, etc.), its universal nature means that it should logically be the king/queen of identity politics, while it has long been the pauper. This story helps explain why that was and is today, and what America’s unique and sometimes unpleasant role in the story is. This text attempt...
REX East Project
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There Goes the Gayborhood?
An in-depth look at America's changing gay neighborhoods Gay neighborhoods, like the legendary Castro District in San Francisco and New York's Greenwich Village, have long provided sexual minorities with safe havens in an often unsafe world. But as our society increasingly accepts gays and lesbians into the mainstream, are "gayborhoods" destined to disappear? Amin Ghaziani provides an incisive look at the origins of these unique cultural enclaves, the reasons why they are changing today, and their prospects for the future. Drawing on a wealth of evidence—including census data, opinion polls, hundreds of newspaper reports from across the United States, and more than one hundred original int...
Mid-America
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The Birth of the Pill
In the winter of 1950, Margaret Sanger, then seventy-one, and who had campaigned for women's right to control their own fertility for five decades, arrived at a Park Avenue apartment building. She had come to meet a visionary scientist with a dubious reputation more than twenty years her junior. His name was Gregory Pincus. In The Birth of the Pill, Jonathan Eig tells the extraordinary story of how, prompted by Sanger, and then funded by the wealthy widow and philanthropist Katharine McCormick, Pincus invented a drug that would stop women ovulating. With the support of John Rock, a charismatic and, crucially, Catholic doctor from Boston, who battled his own church in the effort to win public...
Poisoner in Chief
The bestselling author of All the Shah’s Men and The Brothers tells the astonishing story of the man who oversaw the CIA’s secret drug and mind-control experiments of the 1950s and ’60s. The visionary chemist Sidney Gottlieb was the CIA’s master magician and gentlehearted torturer—the agency’s “poisoner in chief.” As head of the MK-ULTRA mind control project, he directed brutal experiments at secret prisons on three continents. He made pills, powders, and potions that could kill or maim without a trace—including some intended for Fidel Castro and other foreign leaders. He paid prostitutes to lure clients to CIA-run bordellos, where they were secretly dosed with mind-alterin...
