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Biomarkers hold immense promise for the early detection of disease. Unlike other disorders like diabetes and heart disease where a limited number of biological markers are at hand that allow the physician to come up with a reliable diagnosis, there are currently no such markers available for affective disorders. As in any other disease area a major goal is therefore the identification of early markers that can categorize subsets of subjects in a consistent manner. This will allow a more precise definition and categorization of affective disorders and in turn facilitate investigations of the pathogenesis of the diseases and enhance our ability for treatment. This edited volume will not only address the area of affective disorders but also other brain disorders that are neurological in nature, including Multiple Sclerosis and Alzheimer Disease.
Founded by Churchill, Special Operations Executive (SOE) was the forerunner of the SAS, and during WWII they sent many hundreds of specially-trained agents deep undercover in Nazi-occupied Europe. Here Marcus Binney explores the extraordinary stories and daring exploits of some of the male agents who made up these little-known war heroes, and who helped change the course of the twentieth century with their bravery and sacrifice. The author has undertaken ground-breaking research in previously classified Foreign Office files in order to write this book.
Schon lange versuchen Psychiatrie und klinische Psychologie, der Depression auf den Grund zu gehen. In den letzten Jahrzehnten richten sich die Forschungsanstrengungen auf Biomarker, das heißt biologische Parameter, mit denen depressive Erkrankungen greifbar gemacht und im Körper verankert werden sollen. Jonas Rüppel arbeitet mit einem Fokus auf genetische und neurowissenschaftliche Studien heraus, dass diese Suche nach Biomarkern jedoch nicht in der ersehnten körperlichen Fundierung resultiert. Stattdessen mündet die »Biomarkerisierung der Depression« in einer zunehmenden Destabilisierung dieses psychiatrischen Krankheitsbildes. Erkennbar wird ein neues psychiatrisches Dispositiv, das auf eine Dekonstruktion und biowissenschaftliche Neuzusammensetzung der etablierten Krankheitskategorien abzielt: das »postgenomische Prisma«. Lizenzierung: https://creativecommons.org/licenses/by-nc-nd/4.0/