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The Impact of Protein Chemistry on the Biomedical Sciences focuses on the structure, function, and synthesis of proteins. This book examines the various approaches on how amino acids are polymerized in vitro, which involves the physical, chemical, immunological, enzymologic, biosynthetic, and organic synthetic techniques. Comprised of five parts encompassing 27 chapters, this book starts with an overview of Christian B. Anfinsen's role in the development of protein chemistry and the training of scientists who have advanced their experiences in his laboratory to pioneer in the field of biological and medical sciences. This text then examines the synthesis of albumin molecule in the bloodstream as it carries cystine, hematin, bilirubin, fatty acids, and aromatic compounds. Other chapters discuss the kinetic experiments of hydrogen exchange in aqueous solution between peptide molecules and solvent water. This text also introduces the reader to the lipoprotein–atherosclerosis connection by studying the metabolism of plasma lipoproteins. This book is a valuable source of information for biologists, chemical biologists, scientists, and students.
This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric G?n?nproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.
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Each issue lists papers published during the preceding year.
Profiles more than 200 American men and women who made significant contributions to science during the twentieth century.
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This exciting edition of Avila's popular biology textbook offers current, accurate, clearly written and well organized information, including seven new chapters. Written for introductory biology courses, this text represents the philosophy that an understanding of the principles of biology from a cellular perspective is key to a biological literacy and a full appreciation of the many intricacies of life.
A collection of the Nobel Lectures delivered by the prizewinners in chemistry, together with their biographies, portraits and the presentation speeches.