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EEG - fMRI
Functional magnetic resonance imaging (fMRI) and Electronecephalography (EEG) are very important and complementary modalities since fMRI offers high spatial resolution and EEG is a direct measurement of neuronal activity with high temporal resolution. Interest in the integration of both types of data is growing rapidly as it promises to provide important new insights into human brain activity as it has already done so in the field of epilepsy. The availability of good quality instrumentation capable of providing interference-free data in both modalities means that electrophysiological and haemodynamic characteristics of individual brain events can be captured for the first time. Consequently...
Neural Correlates of Thinking
The advances in neuroimaging technologies have led to substantial progress in understanding the neural mechanisms of cognitive functions. Thinking and reasoning have only recently been addressed by using neuroimaging techniques. The present book comprehensively explores current approaches and contributions to understanding the neural mechanisms of thinking in a concise and readable manner. It provides an insight into the state of the art and the potentials, but also the limitations of current neuroimaging methods for studying cognitive functions. The book will be a valuable companion for everyone interested in one of the most fascinating topics of cognitive neuroscience.
Focus on Serotonin Uptake Inhibitor Research
The most significant class of antidepressants marketed in recent years is the selective serotonin re-uptake inhibitors (SSRIs). Claims of decreased adverse effects (ADRs) and increased safety have led to extensive use of these drugs by non-psychiatrists. The six SSRIs available in the United States are citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft). The primary uses for the SSRIs include unipolar and bipolar major depression and all of the anxiety disorders. However, controlled trials also support the use of SSRIs in the treatment of other psychiatric disorders including dysthymia, pre-menstrual dysphoria, bulimia nervosa, obesity, borderline personality disorder, alcoholism, rheumatic pain, and migraine headache. This new book presents leading-edge research from throughout the world on this topic.
The University Department of Psychiatry in Munich
This book first appeared in Germany in 2004. In response to the great amount of interest in the book expressed by colleagues from all over the world, we subsequently decided to produce this English version. We have also taken this opportunity to update the information on the Department of Psychiatry since 1994 to include further developments up to the present day (see Chapter 15). One can look at a hospital from all kinds of different perspectives. For psychiatrists with the daily medical task of dealing with the life histories of their patients, it is understandable that they are interested in the development of their hospital from a historical perspective. To do this for the University Department of Psychiatry of Munich an introduction can be made by reminding the reader of a date: just over 100 years ago, on November 7, 1904, the newly constructed »Royal Psychiatric Hospital of the University of Munich« was inaugurated with a ceremonial act and handed over to the public. Emil Kraepelin gave a ceremonial speech on the occasion.
Third-Generation Neuroimaging: Translating Research into Clinical Utility
Psychiatric imaging needs to move away from simple investigations of the neurobiology underling the early phases of psychiatric diseases to translate imaging findings in the clinical field targeting clinical outcomes including transition, remission and response to preventative interventions. This research topic aims to bring psychiatric neuroimaging studies towards translational impacts in clinical practice, suggesting that brain abnormalities may be of potential use for detecting clinical outcomes as treatment response. First-generation psychiatric neuroimaging focused on simple structural brain alterations associated with the neurobiology of the illness. These early studies adopted imaging...
Advanced Brain Neuroimaging Topics in Health and Disease
The brain is the most complex computational device we know, consisting of highly interacting and redundant networks of areas, supporting specific brain functions. The rules by which these areas organize themselves to perform specific computations have only now started to be uncovered. Advances in non-invasive neuroimaging technologies have revolutionized our understanding of the functional anatomy of cortical circuits in health and disease states, which is the focus of this book. The first section of this book focuses on methodological issues, such as combining functional MRI technology with other brain imaging modalities. The second section examines the application of brain neuroimaging to understand cognitive, visual, auditory, motor and decision-making networks, as well as neurological diseases. The use of non-invasive neuroimaging technologies will continue to stimulate an exponential growth in understanding basic brain processes, largely as a result of sustained advances in neuroimaging methods and applications.
Neuroimaging in Schizophrenia
This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.
Neuromatic
"The story Modern tells ranges from eighteenth-century brain anatomies to the MRI; from the spread of phrenological cabinets and mental pieties in the nineteenth century to the discovery of the motor cortex and the emergence of the brain wave as a measurable manifestation of cognition; from cybernetic research into neural networks and artificial intelligence to the founding of brain-centric religious organizations such as Scientology; from the deployments of cognitive paradigms in electric shock treatment to the work of Barbara Brown, a neurofeedback pioneer who promoted the practice of controlling one's own brainwaves in the 1970s. What Modern reveals via this grand tour is that our ostensibly secular turn to the brain is bound up at every turn with the 'religion' it discounts, ignores, or actively dismisses. Nowhere are science and religion closer than when they try to exclude each other, at their own peril"--
Cognitive Plausibility in Natural Language Processing
This book explores the cognitive plausibility of computational language models and why it’s an important factor in their development and evaluation. The authors present the idea that more can be learned about cognitive plausibility of computational language models by linking signals of cognitive processing load in humans to interpretability methods that allow for exploration of the hidden mechanisms of neural models. The book identifies limitations when applying the existing methodology for representational analyses to contextualized settings and critiques the current emphasis on form over more grounded approaches to modeling language. The authors discuss how novel techniques for transfer and curriculum learning could lead to cognitively more plausible generalization capabilities in models. The book also highlights the importance of instance-level evaluation and includes thorough discussion of the ethical considerations that may arise throughout the various stages of cognitive plausibility research.
