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Tissue Engineering
Tissue engineering is a multidisciplinary field incorporating the principles of biology, chemistry, engineering, and medicine to create biological substitutes of native tissues for scientific research or clinical use. Specific applications of this technology include studies of tissue development and function, investigating drug response, and tissue repair and replacement. This area is rapidly becoming one of the most promising treatment options for patients suffering from tissue failure. This abundantly illustrated and well-structured guide serves as a reference for all clinicians and researchers dealing with tissue engineering issues in their daily practice.
Skin Stress Response Pathways
It is now established that the interplay between environmental exposure and molecular stress response pathways plays a critical role in skin health and disease, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit patients in the near future. Coauthored by recognized international leaders in molecular and clinical biomedical sciences, this novel book provides a comprehensive perspective on environmental exposure-induced skin stress response pathways. Focusing on molecular opportunities targeting skin stress response pathways that are involved in cutaneous barrier function and repair, antimicrobial defense, immune regulation, inflammation, and malignant progression, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in skin health and disease with implications for small molecule therapeutic development.
Methods in Enzymology
Since the inception of the series, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all field of life sciences. This final volume in the five-part Nitric Oxide series supplements MIE volumes 268, 269, 301 and 359. Nitric Oxide impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organic biology, as well as fundamental chemistry. These volumes are a valuable resource for the experienced researcher and for those entering the field. *One of the most highly respected publication in the field of biochemistry since 1955 *Frequently consulted and praised by researchers and reviewers alike *Truly an essential publication for anyone in any field of the life sciences
Nitric Oxide
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Die Verarbeitung von Körpersubstanzen zu autologen Gewebeprodukten nach § 950 BGB
Menschliche Luftröhren oder Herzklappen aus dem Labor sind nicht mehr bloße Zukunftsmusik. Forschergruppen ist es bereits gelungen, diese komplexen Gewebe im Rahmen des sogenannten Tissue Engineering aus menschlichen Körperzellen herzustellen und Menschen erfolgreich zu implantieren. Allgemein wird die Herstellung aus patienteneigenen Zellen angestrebt, da es nach der Implantation des Gewebes zu keiner Abstoßungsreaktion des Körpers kommt. Die Herstellung von menschlichen Geweben kann zu einem gesetzlichen Eigentumserwerb des Herstellers nach § 950 BGB führen. Bei der Verwendung von patienteneigenen Zellen kommt es jedoch zu einem Konflikt zwischen dem entstandenen Eigentum des Herstellers und dem Persönlichkeitsrecht des Patienten. Die Arbeit untersucht zunächst, wann die Voraussetzungen eines solchen Eigentumserwerbs erfüllt sind. Anschließend wird erörtert, wie sich das Eigentum zum allgemeinen Persönlichkeitsrecht verhält und welche Ansprüche zwischen den Beteiligten bestehen.
The Hygiene Hypothesis and Darwinian Medicine
Man has moved rapidly from the hunter-gatherer environment to the living conditions of industrialised countries. The hygiene hypothesis suggests that the resulting reduced exposure to micro-organisms has led to disordered regulation of the immune system, and hence to increases in certain chronic inflammatory disorders, like allergic disorders, autoimmunity, inflammatory bowel disease, atherosclerosis, depression, some cancers and perhaps Alzheimer and Parkinson. This book discusses the evidence for and against in the context of Darwinian medicine, which uses knowledge of evolution to cast light on human diseases. The approach is interdisciplinary, looking at man’s microbiological history, at the biology of the effects of microorganisms on the immune system, and at the implications for chronic inflammatory disorders in multiple organ systems. Finally, the authors describe progress in the exploitation of microorganisms or their components as novel prophylactics and treatments.
