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T Cell Protocols
The purpose of T Cell Protocols: Development and Activation is to c- lect a series of protocols, particularly those that have been developed within the past few years, to help investigators master new techniques (or improve existing ones) for the study of T-cell Biology. Invariably, in putting together a book like this it is difficult to decide which methods to include and which to leave out. To this end methods were selected from a variety of disciplines, including cellular immunology, b- chemistry, and molecular biology, to try to provide something of interest for everyone who works on T-cell development and activation. I would like to mention that my primary reason for agreeing to put thi...
The Black Box of Biology
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology w...
The Roman Imperial Succession
An investigation of how a man could become a Roman emperor, and the failure to create an enduring, consistent system for selecting the next emperor. John D. Grainger analyses the Roman imperial succession, demonstrating that the empire organized by Augustus was fundamentally flawed in the method it used to find emperors. Augustus’s system was a mixture of heredity, senatorial, and military influences, and these were generally antagonistic. Consequently, the Empire went through a series of crises, in which the succession to a previous, usually dead, emperor was the main issue. The infamous “Year of the Four Emperors,” AD 69, is only the most famous of these crises, which often involved ...
Re-Framing Urban Space
Re-framing Urban Space: Urban Design for Emerging Hybrid and High-Density Conditions rethinks the role and meaning of urban spaces through current trends and challenges in urban development. In emerging dense, hybrid, complex and dynamic urban conditions, public urban space is not only a precious and contested commodity, but also one of the key vehicles for achieving socially, environmentally and economically sustainable urban living. Past research has been predominantly focused on familiar models of urban space, such as squares, plazas, streets, parks and arcades, without consistent and clear rules on what constitutes good urban space, let alone what constitutes good urban space in ‘high-...
Wide Field Spectroscopy And The Distant Universe - Proceedings Of The 35th Herstmonceux Conference
Galaxies represent the most readily visible fabric of the cosmos. Their morphological types, luminosities and environmental surroundings contain valuable clues as to their origin and evolution. Locally, a strong correlation is seen between galaxy morphology and environmental location; this may have been molded at surprisingly modest redshifts. Spectroscopic and photometric studies of deep fields also suggest remarkably recent changes in the galaxy population. The associated growth of structure during the same interval can be tracked via X-ray studies of distant clusters of galaxies.Very recently, impressive observational facilities have been completed, each of which has extended the astronom...
Novel Systems for the Study of Human Disease From Basic Research to Applications
This proceedings brings together scientific papers covering the breadth and significance of model animals used in scientific research, and scientific and policy summaries based on workshop discussions.
A Book for the World
The wondrous, yet troubling world is within!
Rome to Florence
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