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New Solutions for the Heart
Although cardiac surgery has made an enormous progress during the last decades, the discipline has to cope with essential changes: Patients are increasingly cared for by cardiologists and therefore referred to the surgeon in a later stage of disease. Consequently, they are more often in an increasingly serious state or in advanced age with significant comorbidities. In order to meet the requirements of these different patient groups, cardiosurgical treatments require special protectional strategies for the heart in order to perform the planned operations safely. This book presents the latest knowledge of modern techniques of myocardial protection taking into consideration the different patient groups and current scientific strategies. Furthermore, it discusses present and future scientific approaches in myocardial protection and preservation.
Antioxidants in Therapy and Preventive Medicine
Twenty years ago, the enzyme superoxide dismutase which uses the superoxide radical anion as its specific substrate was reported. With this discovery was born a new scientific field, in which oxygen, necessary for aerobi c 1 ife on thi s planet, had to be cons i dered also in terms of its toxicity and stresses. This stimulated the search for knowledge of active oxygen species in biology and medicine. Superoxide and other reactive oxygen species are now implicated in many disease processes. Major advances have been achieved during these past years with respect to free radical generation and mechanisms of free radical action in causing tissue injury. In parallel, the possibil ity of influencin...
The Modern Era of Coronary Thrombolysis
Coronary heart disease remains the leading cause of death for men and women in the United States and other industrialized nations. Acute myocardial infarction accounts for a majority of these deaths, approaching 750,000 yearly. Thrombolytic therapy has revolutionized the treatment of myocardial infarction, saving lives to a greater extent than any treatment developed to date. The identification of patients best suited for thrombolytic therapy has been a challenging task, as has the ideal adjuvant strategy. Further, the noninvasic diagnosis of treatment successes and failures, as well as the expeditious triaging of patients requiring mechanical/surgical revascularization have been difficult t...
Towards Safer Cardiac Surgery
D. B. LONGMORE The concept ofthe meeting on which this book is based is unique. There has never be fore been a multi-disciplinary meeting based entirely on the concept of making a major branch of surgery safer. Hopefully, this meeting will be archetypal and will set a precedent for similar attempts in other disciplines as well as future efforts to make cardiac surgery safer. Cardiac surgery is still a rapidly growing discipline even after a quarter of a century of experience. Like any new area of science, or medicine, initially there is an exponential growth ofwork, publications, meetings, options of available equipment and all the ancillary and peripheral disciplines associated with it. The ideas of the handful of original surgical pioneers, some of whom have contributed to this book, formed the basis of a still rapidly growing young branch of surgery with a whole new medical discipline of total extracorporeal circulation involving biochemical and haemodynamic control of a patient.
Membrane Physiopathology
The need for publishing acomprehensive review ofa number ofdifferent membrane pathologiesofmuscleand non-musclecells inillnesses ranging from diabetes toheart disease and cancer lies on to the fact that there are several books dealing with the properties ofnormal cell membranes, although there are very few books focussing on the abnormal membrane behavior. Since the membrane is the critical outer barrier of a cell, this membrane could be the first structure to be affected in some diseases. Research is advancing at the cellular level at a very rapid rate. We can now address questions such as: "How and by what is the mechanism underlying membrane ion channel and receptor dysfunction leading to...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Handbook of Cardiac Anatomy, Physiology, and Devices
This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.
Diagnosis and Treatment of Aortic Diseases
Describes recent surgical techniques developed to improve prognosis in aortic diseases, and discusses recent interventional strategies such as endovascular stent-graft placement and non-surgical reconstruction of the aorta. Chapters deal with aortic dissection, aortic aneurysm, surgical treatment of aortic aneurysms and dissections, inherited disorders of the aorta, aortic trauma, aortitis, and etiology and pathology of aortic malformations. Each chapter is organized in a similar fashion, with information on demographic aspects, pathology, clinical presentation, and diagnostic and therapeutic approaches. Annotation copyrighted by Book News, Inc., Portland, OR
Physiology and Pathophysiology of the Heart
could go on for several pages. Thus the book edited This book emphasizes the fundamental, functional aspects of cardiology. Within the last thirty years, by Sperelakis IS a potent reminder of the almost for the rift between clinical and investigative cardiology gotten fact that cardiology has twO sites, inextrica has widened, because of the overwhelming devel bly related. opment of new clinical procedures, both diagnostic The book deals with subjects in which Dr. Sper and therapeutic. Almost forgotten is the fact that elakis has pioneered: ultrastructure of heart muscle, we owe most of the clinical advances to theoretical electrophysiology, cardiac contractility, and ion ex and experimental ...
