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Development of T Cell Immunity
T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes. This volume reviews the latest developments and discusses the evolution of T cell immunity, thymic requirements, and how to prevent T cell-dependent autoimmunity. - Discusses new discoveries, approaches, and ideas in T cell immunity - Contributions from leading scholars and industry experts - Reference guide for researchers involved in molecular biology and related fields
Power Struggles
Power Struggles: Hydro Development and First Nations in Manitoba and Quebec examines the evolution of new agreements between First Nations and Inuit and the hydro corporations in Quebec and Manitoba, including the Wuskwatim Dam Project, Paix des Braves, and the Great Whale Project. In the 1970s, both provinces signed so-called “modern treaties” with First Nations for the development of large hydro projects in Aboriginal territories. In recent times, however, the two provinces have diverged in their implementation, and public opinion of these agreements has ranged from celebratory to outrage. Power Struggles brings together perspectives on these issues from both scholars and activists. In debating the relative merits and limits of these agreements, they raise a crucial question: Is Canada on the eve of a new relationship with First Nations, or do the same colonial attitudes that have long characterized Canadian-Aboriginal relations still prevail?
Medical Neurobiology
Medical Neurobiology explains the fundamentals of the nervous system as it relates to human health. The text uses everyday examples to clarify neural function. The contribution of the nervous system to diverse and common medical disorders such as Parkinson's disease, hearing loss.myopia, hypertension, and asthma are explored.
By Force and Fear
An unwilling, desperate nun trapped in the cloister, unable to gain release: such is the image that endures today of monastic life in early modern Europe. In By Force and Fear, Anne Jacobson Schutte demonstrates that this and other common stereotypes of involuntary consignment to religious houses—shaped by literary sources such as Manzoni’s The Betrothed—are badly off the mark. Drawing on records of the Congregation of the Council, held in the Vatican Archive, Schutte examines nearly one thousand petitions for annulment of monastic vows submitted to the Pope and adjudicated by the Council during a 125-year period, from 1668 to 1793. She considers petitions from Roman Catholic regions a...
Experimental and Applied Immunotherapy
Immunotherapy is now recognized as an essential component of treatment for a wide variety of cancers. It is an interdisciplinary field that is critically dependent upon an improved understanding of a vast network of cross-regulatory cellular populations and a diversity of molecular effectors; it is a leading example of translational medicine with a favorable concept-to-clinical-trial timeframe of just a few years. There are many established immunotherapies already in existence, but there are exciting new cancer immunotherapies just on the horizon, which are likely to be more potent, less toxic and more cost effective than many therapies currently in use. Experimental and Applied Immunotherap...
Minor Histocompatibility Antigens
With the widespread application of solid tissue and bone marrow transplantation as a treatment for an array of life threatening disorders, there is a pressing need for clinicians and experimentalists to understand the basis of immunological rejection of tissue transplants. While much previous work focuses on characterization of antigens encoded by
