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Thymic Stromal Alterations and Genetic Disorders of Immune System
  • Language: en
  • Pages: 83

Thymic Stromal Alterations and Genetic Disorders of Immune System

The pathogenic mechanisms underlying primary T-cell disorders are mainly related to molecular alterations of genes whose expression is intrinsic to hematopoietic cells. However, since the differentiation process requires a crosstalk among thymocytes and the thymic microenvironment, molecular alterations of genes, involved in the differentiation and functionality of the stromal component of the thymus, may lead to a severe T-cell defect or failure of central tolerance, as well. The first example of severe combined immunodeficiency (SCID) not related to an intrinsic alteration of the hematopoietic cell but rather of the thymic epithelial component is the Nude/SCID phenotype, inherited as an au...

Pediatric Immunology
  • Language: en
  • Pages: 792

Pediatric Immunology

This book comprises a collection of categorized case-based questions, directed and meticulously selected to cover the most common and most important aspects of immunodeficiency diseases. Immunodeficiency disorders of infancy and childhood such as antibody deficiencies, phagocyte defects and defects in innate immunity are addressed among others. Each chapters starts with a brief of the initial presentation and lab data of the patient, followed by a series of 5-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. This MCQ format along with precise, yet detailed answer ensures a quick, case-based, reality learning to the reader. This comprehensive MCQ series, is an essential reading material that a pediatric clinician, hematologist, immunologist, transplant specialist, or pulmonologist, can not afford to miss.

Forum
  • Language: en
  • Pages: 714

Forum

  • Type: Book
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  • Published: 1995
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  • Publisher: Unknown

None

New Insights into Thymic Functions during Stress, Aging, and in Disease Settings
  • Language: en
  • Pages: 228

New Insights into Thymic Functions during Stress, Aging, and in Disease Settings

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Autophagy in Autoimmunity
  • Language: en
  • Pages: 161

Autophagy in Autoimmunity

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Rare Cardiovascular Diseases, An Issue of Heart Failure Clinics, E-Book
  • Language: en
  • Pages: 225

Rare Cardiovascular Diseases, An Issue of Heart Failure Clinics, E-Book

In this issue of Heart Failure Clinics, Guest Editors Giuseppe Limongelli and Eduardo Bossone bring their considerable expertise to the topic of rare cardiovascular diseases. Top experts in the field cover key topics such as coronary artery dissection, genetics in congenital heart disease, HCM in Rasopathies, and more. - Provides in-depth, clinical reviews on Rare Cardiovascular Diseases, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 17 relevant, practice-oriented topics including The influence of genotype on the phenotype, clinical course, and risk of adverse events in children with Hypertrophic cardiomyopathy; Unravelling the genetic background in heritable and non-heritable BAV: a long roadmap; The risk of sudden unexpected cardiac death in children: epidemiology, clinical causes, and prevention; The renal involvement in patients with storage and infiltrative cardiomyopathies; and more.

The contributions of the MUNA network to CUCS Naples 2022. Proceedings of MUNA sessions: CUCS_Coordinamento Universitario per la Cooperazione allo Sviluppo, Naples 21st-23rd April 2022
  • Language: en
  • Pages: 232

The contributions of the MUNA network to CUCS Naples 2022. Proceedings of MUNA sessions: CUCS_Coordinamento Universitario per la Cooperazione allo Sviluppo, Naples 21st-23rd April 2022

[Italiano]: Il Consortium Muna (Mediterranean and Middle East University Network Agreement) è stato fondato nel 2015 e rinnovato nel 2021, quando 30 Università provenienti da tutti i Paesi dell'area mediterranea e alcune altre dal Medio Oriente hanno firmato l'Accordo Quadro. Come scritto nell'Accordo Quadro, anche in questo spazio Muna della Conferenza CUCS, proponiamo tre diversi temi principali: MARE NOSTRUM (il nostro Mare, il Mediterraneo), PERSONA (l'Uomo) e ORBIS (la Terra), per riassumere le proposte di Cooperazione tra le Università di Muna Network. La prima sessione è dedicata al campo di ORBIS per condividere la sostenibilità, attraverso la biodiversità come elemento chiave ...