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This book contains notable contributions from the well-known Vicenza course on hemodialysis and miniaturized wearable devices for renal replacement therapy. The main themes covered in this publication include cardio-renal syndromes as well as new technologies in hemodialysis, new dialysis membranes and techniques, the importance of vitamin D receptors in renal and extra-renal physiology, and the control of risk factors such as blood pressure and lipid disorders. Special interest is placed on new models of organization including large dialysis networks and health care economics. Moreover, acute kidney injury and its impact on the subsequent development of chronic kidney disease are discussed together with the use of modern biomarkers. Microfluidics, nanotechnology and miniaturized dialysis devices suitable for wearable ambulatory treatments are also covered in depth. The publication at hand is a useful tool for consultation by the clinician as well as for those involved in the care of patients with end-stage kidney disease.
This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings together experts at the nexus between cardiovascular and renal medicine to provide an exception reference to educate in this critical area of modern medicine. It describes how the heart and kidneys are inextricably linked via hemodynamic, neural, hormonal and cellular signaling systems and, concentrating on disease-based coverage, goes on to review emerging concepts in epidemiology, pathogenesis, screening, diagnosis and the management of cardiorenal syndromes, all extensively illustrated and containing features to support scholarship in the field. Textbook of Cardiorenal Medicine provides consistent chapter organization, clear design and engaging text to define the diagnosis, treatment, intervention and surgical aspects of the full range of conditions encountered within this area of medicine. It is therefore an essential resource to all involved in the management of cardiorenal disease.
Telemedicine and remote patient monitoring are innovative tools to provide remote transmission, interpretation, and storage of data for review by the care team. These tools allow for accurate home monitoring of patients enabling the team to improve care through prevention and early identification of problems. This book is structured into four main parts. The first describes the evolution of peritoneal dialysis and related technology. The second part summarizes current unmet clinical needs reported by patients and care teams, the need for innovation in the field, and the technical and clinical issues involved with the modern management of peritoneal dialysis. The third section presents the op...
Internists, surgeons, critical care physicians and nephrologists all treat critically ill patients with renal failure and the multiple system organ dysfunction syndrome. A comprehensive review of the state of the art of this topic is definitely needed both in academic and clinical medicine, and Critical Care Nephrology fulfils this need. It is a useful reference tool for both nephrologists and intensive care specialists and it is therefore no coincidence that the editors of the book are themselves specialists in these particular fields. The book addresses the following: definitions of critical illness, epidemiology, monitoring and diagnostic procedures, pathophysiology of organ systems in re...
Extending from the outpatient management of cardiovascular and kidney disease, to hospital-based decision making in patients with cardio-renal disease and complex interfaces such as hemodialysis in patients with ventricular assist device support, this book serves as a single reference point for cardiology and nephrology clinicians and researchers dealing with the significant overlap areas between these two specialties. Chapters cover the physiology, biomarkers, therapeutic agents and full spectrum of these comorbidities and feature separate sections on cardiovascular and CKD evaluations, stratification of kidney transplant patients, lipid management in CKD, interventional strategies and hypertension. Leaders in cardiology, nephrology, hypertension and lipidology bring together the latest evidence with their collective clinical experience into this invaluable resource.This textbook is an essential resource for physicians and allied professionals practicing cardiology, nephrology, students and physician trainees, to deepen their understanding of this crucial field.
Despite constant significant advances, cardiovascular as well as more general outcomes of hemodialysis treatment remain unsatisfactory. The introduction of innovative 'high retention onset' membranes has led to the development of a new treatment modality called 'expanded hemodialysis' (HDx), which is the focus of this book. This new therapy is likely to benefit end-stage kidney disease patients, thanks to enhanced removal of molecules retained by current dialysis techniques. HDx is simple to set up and application does not require special hardware or specific nursing skills. This book contains emerging evidence and fascinating new hypotheses on HDx. It is highly recommended for all physicians and healthcare professionals who are caring for dialysis patients and are seeking innovation and improved care solutions. It will also be of considerable interest to students and fellows.
Acute kidney failure is an important clinical area in the intensive care unit setting. An estimated 5–20% of critically ill patients experience an episode of acute kidney failure during the course of their illness, and about 5% of patients admitted to an ICU will eventually require renal replacement therapy. In these patients, in-hospital mortality is extremely high, exceeding 50%. Thus, the early detection and causal treatment of acute kidney problems is vitally important for a successful outcome. Written by internationally renowned experts, this clinical reference offers helpful advice with the most recent information on the definition, epidemiology, pathophysiology, and clinical causes ...
Te practice of intensive care medicine is at the very forefront of titration of treatment andmonitoringresponse. Te substrateofthiscareisthe criticallyill patientwho,by defnition, is at the limits of his or her physiologic reserve. Such patients need immediate, aggressive but balanced life-altering interventions to minimize the detrimental aspects of acute illness and hasten recovery. Treatmentdecisionsandresponsetotherapyareusually assessed by measures of physiologic function, such as assessed by cardio-respiratory monitoring. However, how one uses such information is ofen unclear and rarely supported by prospective clinical trials. In reality, the bedside clinician is forced to rely primar...
The field of hemodialysis is subject to constant transformations due to continuous advances in techniques, biomaterials and devices. Based on international surveys, objective evaluations of experts and recent clinical trials, the publication at hand pays special attention to the physiological aspects of treatments as well as practical questions in the dialysis unit. Taking into account recent developments, an international group of contributors addresses issues related to vascular access, epidemiology, inflammation, fluid management, uremic toxicity, treatment efficacy, advanced techniques, calcium/phosphate homeostasis, and correction of anemia. Focusing on basic and clinical aspects of innovative technology as well as on new therapeutic options, this publication is a most helpful tool for the clinician to keep abreast of developments in the field of hemodialysis.
Acute organ damage and the ensuing multiple organ failure are the result of a pathophysiological process involving various cytokines. Once activated, these proteins cannot be eliminated even when the kidneys function at their maximum capacity. To counteract this mechanism, researchers in Japan have developed an innovative concept employing blood purification to remove the overwhelming cytokines.This book describes the use of hemodiafiltration to inhibit the cytokine storms which cause serious organ damage in patients with septic shock. Moreover, the technical construction of the blood purification system, which includes various machines, devices, membranes, fluids, etc., is explained in detail. Finally, leading experts discuss the concept of continuous renal replacement therapy as the standard care in critically ill patients with severe acute kidney injury.Describing the current state of acute blood purification, this publication provides new impulses and opens new avenues in the treatment of acute organ damage.