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The advances and technical improvements of X-ray imaging techniques, taking advantage of X-ray focussing optics and high intensity synchrotron sources, nowadays allow for the use of X-rays to probe the cellular nanoscale. Importantly, X-rays permit thick samples to be imaged without sectioning or slicing. In this work, two macromolecules, namely keratin intermediate filament (IF) proteins and DNA, both essential components of cells, were studied by X-ray techniques. Keratin IF proteins make up an integral part of the cytoskeleton of epithelial cells and form a dense intracellular network of bundles. This network is built from monomers in a hierarchical fashion. Thus, the keratin structure fo...
A definitive one-volume guide to all sub-Saharan African countries, providing invaluable economic and directory data.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
A one-volume library of essential and comprehensive data on all the countries of sub-Saharan Africa, including essays on regional issues, statistical surveys and directories of invaluable contact names and addresses
Juin 1944. Alors que les semaines d’occupation allemande semblent désormais comptées, la vie d’un bourg du sud de la Haute-Marne est brusquement ébranlée par deux affaires tragiques : un maquis tout juste constitué est décimé et, simultanément, une vague d’arrestations par la Gestapo touche la population locale. Y a-t-il corrélation entre les deux événements ? Aucun doute n’est permis sur les raisons du massacre des jeunes résistants : ils ont été victimes d’une trahison. Cécile, la fille du quincaillier, en sort profondément meurtrie. A la Libération, comme plusieurs de ses proches, elle a soif de vérité et de justice. Qui est vraiment ce compagnon-charpentier un peu taciturne, étranger au pays ? La trahison demeurera-t-elle impunie ?
"An authoritative and clearly written survey, giving an in-depth coverage over a wide field". -- Reference Reviews New Edition This vital source of up-to-date information provides essays on topics of concern to Africa as a whole, details on international and regional organizations active in Africa and surveys and directories for each African nation. For each country, signed articles cover its physical and social geography, recent history and economy. Following the articles are statistical surveys covering national development, economic status, population, administration, religion, communications and many other subjects.
"Ypt/Rab GTPases form the largest branch of the Ras-related small GTPase superfamily and regulate intracellular membrane trafficking in all eukaryotes. Since their discovery over two decades ago, a wealth of information has accumulated about the roles that"