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An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Principles and Practice of Pediatric Neurosurgery, Third Edition is a completely revised edition of the most authoritative guide to the management of pediatric neurosurgical disorders encountered in clinical practice. Written by leaders in the field, it provides pediatric neurosurgeons with a clear understanding of the current standards of practice and treatment in the subspecialty. Key Features: Now in full color, with more than 1,000 images An increased emphasis on clinical management strategies in pediatric neurosurgery Seven new chapter topics, including cellular therapy for pediatric neurosurgical disease, conjoined twins, lipomeningoceles, and skeletal syndromes Pearls and pitfalls in every chapter This book is an essential reference for all residents and practitioners in pediatric neurosurgery and pediatric neurology.
Advances in Anticancer Agents in Medicinal Chemistry is an exciting eBook series comprising a selection of updated articles previously published in the peer-reviewed journal Anti-Cancer Agents in Medicinal Chemistry. The second Volume of this eBook series gathers updated reviews on several classes of molecules exhibiting anticarcinogenic potential as well as some important targets for the development of novel anticancer drugs.
With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the r...
Medical diagnosis of tissue anomalies, particularly cancer, is often limited by the constraints of current imaging technologies. This book introduces two approaches to address this issue: the imaging and the non-imaging methods. In the imaging category, the book unveils a pioneering technique based on radio tomosynthesis. Initially proven effective in detecting breast anomalies, this imaging method is now under evaluation for its potential in identifying brain anomalies. For non-imaging diagnostics, it delves into Fourier-transform infrared spectroscopy (FTIR), a technique known for its speed and reliability. The book demonstrates its successful application in diagnosing a range of cancers, including oral, uterine, ovarian, gastrointestinal, colorectal, and skin cancers. Furthermore, it explores its utility in predicting embryo quality and assessing pressure injuries. To augment these methods, the book employs machine learning algorithms, evaluating their efficacy in creating discriminative models for tissue anomalies.
‘A fascinating and wide-ranging account of what neurosurgery is really about – the past, present and future.’ Henry Marsh, author of Do No Harm Since its inception in the early twentieth century, brain surgery has maintained an air of mystery. As the saying ‘it’s not exactly brain surgery’ suggests, the specialty has become synonymous with a level of complexity and meticulousness rivalled only by, well, rocket science. Warm, rigorous and deeply insightful, neurosurgeon Theodore Schwartz reveals what it’s really like to get inside someone’s head – where every second can mean the difference between life or death. Drawing from Schwartz’s experience in one of New York’s busiest hospitals, Gray Matters explores the short but storied history of brain surgery. From the dark days of the lobotomy to the latest research into the long-term effects of contact sports on athletes’ cerebral health, Schwartz unfolds the fascinating story of how we came to understand this extraordinary, three-pound organ, which not only keeps us alive, but makes us who we are.
St. Louis has been the heartbeat of American soccer for years, dominating in club, high school, and college soccer. To this day, St. Louis University has the most NCAA Division I men's soccer national championship titles. Yet, in 1996, when Major League Soccer kicked off its inaugural season, there was no team to represent the Gateway to the West. How did this happen? Author Shane Stay guides you through St. Louis soccer's journey, from its past to the present, including the launch of St. Louis CITY SC. The story will start 100 years in the past and follow the major achievements—and setbacks—of St. Louis soccer. Shane recounts not only the history of soccer at the club, high school, college, and professional levels, but he also provides some helpful hints for which are the best local attractions for soccer fans, and he even goes so far as to predict the future successes of St. Louis CITY SC. This is one book soccer fans will want to have on their shelves!
This resource is intended to provide healthcare providers with a framework to evaluate, treat, and manage the individual needs and preferences of patients with low back pain (LBP). Additionally, this guideline covers all aspects of patient care, including but not limited to, diagnosis, treatment and management. The goal of this reference is to improve the patient's health and wellbeing by providing evidence-based guidance to providers who are diagnosing or treating patients with low back pain. Lower back pain (LBP) is often categorized as acute pain (up to four weeks), subacute pain (4-12 weeks), or chronic pain (more than 12 weeks). Implementation of this guideline is intended to be patient...
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American Association for Cancer Research 2019 Proceedings: Abstracts 1-2748 - Part A