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Computational Analysis of the Mammalian Cis-regulatory Landscape
Improvements in DNA sequencing technologies have made it possible to determine the genetic makeup of many organisms. Computational analyses of the massive amounts of sequence data available have produced many insights into evolutionary and developmental biology. For example, comparison of the full genome sequences of human and mouse discovered that the majority of functional sequence in the human genome does not code for protein. Much of this functional non-coding sequence appears to act in a regulatory role, dictating the precise tissues and developmental time points in which each protein should be produced. This dissertation describes three major contributions to the computational analysis...
Computational Analysis of the Mammalian Cis-regulatory Landscape
Improvements in DNA sequencing technologies have made it possible to determine the genetic makeup of many organisms. Computational analyses of the massive amounts of sequence data available have produced many insights into evolutionary and developmental biology. For example, comparison of the full genome sequences of human and mouse discovered that the majority of functional sequence in the human genome does not code for protein. Much of this functional non-coding sequence appears to act in a regulatory role, dictating the precise tissues and developmental time points in which each protein should be produced. This dissertation describes three major contributions to the computational analysis...
Epidemic Modeling Techniques for Smallpox
Infectious disease models predict the impact of outbreaks. Discrepancies between model predictions stem from both the disease parameters used and the underlying mathematics of the models. Smallpox has been modeled extensively in recent years to determine successful response guidelines for a future outbreak. Five models, which range in fidelity, were created for this thesis in an attempt to reveal the differences inherent in the mathematical techniques used in the models. The disease parameters were standardized across all models. Predictions for various outbreak scenarios are given, and the strengths and weaknesses of each modeling technique are discussed. The mixing strategy used greatly affects the predictions of the models. The results gathered indicate that mass vaccination should be considered as a primary response technique in the event of a future smallpox outbreak.
Self Portrait in Green
'NDiaye is a hypnotic storyteller with an unflinching understanding of the rock-bottom reality of most people's life.' New York Times ' One of France's most exciting prose stylists.' The Guardian. Obsessed by her encounters with the mysterious green women, and haunted by the Garonne River, a nameless narrator seeks them out in La Roele, Paris, Marseille, and Ouagadougou. Each encounter reveals different aspects of the women; real or imagined, dead or alive, seductive or suicidal, driving the narrator deeper into her obsession, in this unsettling exploration of identity, memory and paranoia. Self Portrait in Green is the multi-prize winning, Marie NDiaye's brilliant subversion of the memoir. Written in diary entries, with lyrical prose and dreamlike imagery, we start with and return to the river, which mirrors the narrative by posing more questions than it answers.
To the Warm Horizon
A group of Koreans are making their way across a disease-ravaged landscape—but to what end? To the Warm Horizon shows how in a post-apocalyptic world, humans will still seek purpose, kinship, and even intimacy. Focusing on two young women, Jina and Dori, who find love against all odds, Choi Jin-young creates a dystopia where people are trying to find direction after having their worlds turned upside down. Lucidly translated from the Korean by Soje, this thoughtful yet gripping novel takes the reader on a journey through how people adjust, or fail to adjust, to catastrophe.
Chinese Gung Fu
This new edition of Bruce Lee's classic work rejuvenates the authority, insight, and charm of the master's original 1963 publication for modern audiences. It seemlessly brings together Lee's original language, descriptions and demonstrations with new material for readers, martial arts enthusiasts and collectors that want Lee in his purest form. This timeless work preserves the integrity of Lee's hand-drawn diagrams and captioned photo sequences in which he demonstrates a variety of training exercises and fighting techniques, ranging from gung fu stances and leg training to single- and multiple-opponent scenarios. Thought-provoking essays on the history of gung fu, the theory of yin and yang, and personal, first-edition testimonials by James Y. Lee, the legendary Ed Parker, and jujutsu icon Wally Jay round out this one and only book by Lee on the Chinese martial arts. -- from back cover.
Home Reading Service
In this poignant novel, a man guilty of a minor offense finds purpose unexpectedly by way of his punishment—reading to others. After an accident—or “the misfortune,” as his cancer-ridden father’s caretaker, Celeste, calls it—Eduardo is sentenced to a year of community service reading to the elderly and disabled. Stripped of his driver’s license and feeling impotent as he nears thirty-five, he leads a dull, lonely life, chatting occasionally with the waitresses of a local restaurant or walking the streets of Cuernavaca. Once a quiet town known for its lush gardens and swimming pools, the “City of Eternal Spring” is now plagued by robberies, kidnappings, and the other myriad ...
Killing the Water
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Historical Dictionary of Hong Kong Cinema
Hong Kong cinema began attracting international attention in the 1980s. By the early 1990s, Hong Kong had become "Hollywood East" as its film industry rose to first in the world in per capita production, was ranked second to the United States in the number of films it exported, and stood third in the world in the number of films produced per year behind the United States and India. This second edition of Historical Dictionary of Hong Kong Cinema contains a chronology, an introduction, and an extensive bibliography. The dictionary section has over 600 cross-referenced entries on directors, producers, writers, actors, films, film companies, genres, and terminology. This book is an excellent resource for students, researchers, and anyone wanting to know more about Hong Kong cinema.
