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Cytochromes P450
First published in 1996: An in-depth book on the role of cytochrome P450 proteins from a toxicological perspective, Cytochromes P450: Metabolics and Toxicological Aspects examines the proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals.
Cytochromes P450
Cytochromes P450: Metabolic and Toxicological Aspects examines cytochrome P450 proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. Studying the function of these proteins enables us to: Predict the pathways and outcome of chemical metabolism to rationalize species, sex, and age differences in toxicity Anticipate drug interactions Modify doses to fit the needs of patients Contributions from internationally acknowledged experts are organized into three sections. The first section provides an overview, the next profiles each of the cytochrome P450 families and subfamilies involved in chemical metabolism, and the last section discusses new issues and developments of current interest. This detailed and thorough examination of cytochrome P450 will be a useful source for research scientists, especially those working in the pharmaceutical industry, dealing with the safety evaluation of chemicals and the study of their metabolism, pharmacokinetics, and toxicological properties.
Costas M. Proussis
None
Chemical Safety
How safe is safe enough? We live in a world that is totally dependent on chemicals, be they agrochemicals, pharmaceuticals, colorants - it is vitally important that we adopt a sustainable strategy for an environment containing some 11 million chemicals. This book provides a pragmatic guide to the basic tools of chemical safety assessment, from information retrieval, through hazard and risk assessment to safety evaluation and legal aspects. It is truly global in coverage with contributors drawn from East and West, North and South. It covers natural and artificial hazards to the environment, including the potentially catastrophic effects of modern warfare, and encompasses pollution of air, water and soil as well as occupational exposure to chemicals. Everyone with a professional interest in pollution control will find this an invaluable source of information - chemists, environmental scientists, chemical engineers, political scientists, toxicologists, ecotoxicologists, in industry, academia, government departments and international agencies - all will be guided and challenged by the wealth of knowledge it contains.
Music in Cyprus
Music in Cyprus draws its authors from both sides of the divided island to give a rounded picture of musical culture from the beginning of the British colonial period (1878-1960) until today. The book crosses conventional scholarly divides between musicology and ethnomusicology in order to achieve a panorama of music, culture and politics. Shared practices of traditional music and dance are outlined, and the appropriation of those practices by both communities in the aftermath of the de facto division of the island is examined. Art music (European and Ottoman) is also discussed, both in terms of the structures of musical life and the creative praxes of composers, and there is an account of t...
Environmental Science and Technology
Formally established by the EPA nearly 15 years ago, the concept of green chemistry is beginning to come of age. Although several books cover green chemistry and chemical engineering, none of them transfer green principles to science and technology in general and their impact on the future. Defining industrial ecology, Environmental Science and Tec
Cyprus Blue Book
None
Cytochromes P450
During half a century, cytochrome P450 in its original uniqueness as an optically "wrong" cytochrome has attracted many investigators, who have contributed to the unveiling of a bewildering multiplicity of biologically important functions of the, by now very large, superfamily of cytochrome P 450 enzymes. With its discovery in 1958 and with the advent of more refined spectroscopic methodologies, through the double wavelength spectrophotometry, the mysterious enzyme system began to reveal its secrets in a swift stream of investigative successes. As one of the most extensively studied enzyme systems worldwide the interest in cytochromes P450 very much reflects its importance in the elimination...
Foreign Relations of the United States
According to the National Notary Association, there are 4.8 million notaries working in the U.S. Depending upon state regulations, notaries can perform marriages, witness and authenticate the signing of real estate mortgage loan documents and other legal contracts, and take and certify depositions. Notaries can make an average of $10 to $200 per signing, depending on the document type.Each state has individual guidelines that one must follow when first applying to become a notary and specific restrictions that a practicing notary must abide by, including the amount a notary can charge per signing. With all of these rules, it can be quite a confusing process, and along with the frustration of...
