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Sex Bias in Autoimmunity: From Animal Models to Clinical Research and Applications
Autoimmune diseases are characterized by an abnormal and self-directed immune response leading to damage and dysfunction of multiple organs and tissues. Most autoimmune diseases are recognized as affecting disproportionately more women than men, suggesting a crucial role of sex hormones in modulating immune responses, with estrogens being postulated as enhancing autoimmunity and androgens playing a protective role. It is also widely acknowledged that there is an overwhelming male bias in non-human (animal) studies of autoimmune diseases, while studies of both sexes in human research frequently fail to analyze results by sex. Underrepresentation of females in animal models of autoimmune disea...
Textbook of Pediatric Rheumatology E-Book
Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease. - Offers expanded coverage of autoinflammatory diseases, plus new chapt...
Oxford Textbook of Sjögren's Syndrome
Oxford Textbook of Sjögren's Syndrome is an authoritative resource for everyday practice and reference. Suitable for rheumatologists, ophthalmologists, oral physicians, specialist nurses, neurologists, oncologists, general medics, and dentists.
Artificial Intelligence in Clinical Practice
Artificial Intelligence in Clinical Practice: How AI Technologies Impact Medical Research and Clinics compiles current research on Artificial Intelligence within medical subspecialties, helping practitioners with diagnosis, clinical decision-making, disease prediction, prevention, and the facilitation of precision medicine. The book defines the basic concepts of big data and AI in medicine and highlights current applications, challenges, ethical issues, and biases. Each chapter discusses AI applied to a specific medical subspecialty, including primary care, preventive medicine, general internal medicine, radiology, pathology, infectious disease, gastroenterology, cardiology, hematology, onco...
The Heart in Rheumatic, Autoimmune and Inflammatory Diseases
The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced ...
