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Applied Biophysics for Drug Discovery
Applied Biophysics for Drug Discovery is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns. This text emphasizes practical considerations for selecting and deploying core biophysical method, including but not limited to ITC, SPR, and both ligand-detected and protein-detected NMR. Topics covered include: • Design considerations in biophysica...
The Chemistry, Biology and Medical Applications of Hyaluronan and Its Derivatives
The aim of this book is to collect within one volume information on hyaluronan. This polysaccharide has received rapid attention for two reasons: it has important regulative functions within cell biology; and it has become a commercially important product because of its use in ophthalmic surgery and treatment of joint diease. A number of other practical applications are also discussed. The book covers various aspects of hyaluronan from the structure and chemistry of the polymer to its metabolism, cell biological interactions, behaviour in pathological processes, and potentially new medical applications.
Computational Modeling and Data Analysis in COVID-19 Research
This book covers recent research on the COVID-19 pandemic. It includes the analysis, implementation, usage, and proposed ideas and models with architecture to handle the COVID-19 outbreak. Using advanced technologies such as artificial intelligence (AI) and machine learning (ML), techniques for data analysis, this book will be helpful to mitigate exposure and ensure public health. We know prevention is better than cure, so by using several ML techniques, researchers can try to predict the disease in its early stage and develop more effective medications and treatments. Computational technologies in areas like AI, ML, Internet of Things (IoT), and drone technologies underlie a range of applic...
Biodiversity
Australians have stewardship of a beautiful, diverse and unique environment. We have long had a sense that the biodiversity of this country is special. Yet, despite our sense of its importance, in many parts of our country biodiversity is in trouble. Given the economic, ecological and social importance of biodiversity to our nation, CSIRO has been conducting research into Australia's biodiversity for nearly 90 years. This research has not simply focused on quantifying the challenge, but also on identifying practical solutions for its sustainable management. Biodiversity: Science and Solutions for Australia aims to provide access to the latest scientific knowledge on Australia’s biodiversit...
The Northeastern Reporter
Includes the decisions of the Supreme Courts of Massachusetts, Ohio, Indiana, and Illinois, and Court of Appeals of New York; May/July 1891-Mar./Apr. 1936, Appellate Court of Indiana; Dec. 1926/Feb. 1927-Mar./Apr. 1936, Courts of Appeals of Ohio.
