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James Patterson's blockbuster Alex Cross series has sold over 100 million copies—and now he's bringing those thrills to a new generation! Alex's son Ali is eager to follow in his father's footsteps as a detective, but when his best friend goes missing, what price will he have to pay to solve the mystery? Ali Cross has always looked up to his father, former detective and FBI agent Alex Cross. While solving some of the nation's most challenging crimes, his father always kept his head and did the right thing. Can Ali have the same strength and resolve? When Ali's best friend Gabe is reported missing, Ali is desperate to find him. At the same time, a string of burglaries targets his neighborhood—and even his own house. With his father on trial for a crime he didn't commit, it's up to Ali to search for clues and find his friend. But being a kid sleuth isn't easy—especially when your father warns you not to get involved!—and Ali soon learns that clues aren't always what they seem. Will his detective work lead to a break in Gabe's case or cause even more trouble for the Cross family?
Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.
Alex Cross was a rising star in Washington, DC, Police Department when an unknown shooter killed his wife, Maria, in front of him. Years later, having left the FBI and returned to practising psychology in Washington, DC, Alex finally feels his life is in order... Until his former partner, John Sampson, calls in a favour. John's tracking a serial rapist in Georgetown and he needs Alex to help find this brutal predator. When the case triggers a connection to Maria's death, could Alex have a chance to catch his wife's murderer? Will this be justice at long last? Or the endgame in his own deadly obsession?
"This volume displays de Haume's body of work through four compelling themes: Politics and Play, comprising pieces with titles such as Gorbachev Cross and Superhero Cross; Fashion and Fancy, including tributes to the great fashion houses such as Chanel, Hermès, and Louis Vuitton; Poets and Painters, honoring Donne, Hemingway, Schnabel, Warhol, and many more; and Saints and Saintly, venerating not only saints such as St. Dominic and St. Catherine of Alexandria but also saint-like individuals including humanitarian Raoul Wallenberg--"Publisher's description.
SOON TO BE AN ORIGINAL AMAZON PRIME SERIES ________________________________________ 'Sensationally plotted, it leaps off the page and grabs you by the throat' DAILY MAIL 'No one gets this big without amazing natural storytelling talent - which is what Jim has, in spades. The Alex Cross series proves it.' LEE CHILD 'Alex Cross is a legend.' HARLAN COBEN __________________________________ THE SUNDAY TIMES BESTSELLER Could a ghost from his past take everything away from Alex Cross? Only hours after witnessing the execution of a killer he helped put behind bars, Alex Cross is called to the scene of a copycat murder. A note signed 'M' rests on the corpse: 'You messed up big time, Dr. Cross.' Was ...
Cultural Tourism remains the only book to bridge the gap between cultural tourism and cultural and heritage management. The first edition illustrated how heritage and tourism goals can be integrated in a management and marketing framework to produce sustainable cultural tourism. The current edition takes this further to base the discussion of cultural tourism in the theory and practice of cultural and heritage management (CM and CHM), under the understanding that for tourism to thrive, a balanced approach to the resource base it uses must be maintained. An ‘umbrella approach’ to cultural tourism represents a unique feature of the book, proposing solutions to achieve an optimal outcome fo...
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(Young) lives are cross-sectoral by nature, and youth policy also needs to be so. Cross-sectorality is a well-known aspect of youth policy, but the importance of this aspect does not translate into a common understanding of what cross-sectoral youth policy means and of the ways it can be developed. This book is a collection of articles detailing concrete experiences of cross-sectoral youth policy implementation. It starts with the idea that the efficacy and the sustainability of cross-sectoral youth policy depends on the degree and nature of interaction between various youth policy subdomains and levels, ranging from legal frameworks to interinstitutional or interpersonal relations, and from...