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Phosphazenes
The main aim of this book is to provide a complete picture of current research on phosphazene compounds carried out around the world. The book opens with a general introduction, then moves on to cover synthetic aspects of phosphazene polymers, their characterization in solution and from the theoretical, thermal, and mechanical points of view; application aspects of poly(organophosphazenes); and the synthesis, characterization, and practical utilization of cyclophosphazenes. There is particular focus on the use of cyclophosphazenes as hydraulic fluids and additives, as cores for star polymers or dendrimers, and as starting substrates for supramolecular chemistry and nanostructured materials. The spectroscopic characterization of these compounds by NMR and Raman techniques is also discussed. Annotation : 2004 Book News, Inc., Portland, OR (booknews.com).
Practical Process Research and Development
Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights:• Reflects the current thinking in chemical process R&D for small molecules• Retains similar structure and orientation to the first edition. • C...
Handbook for Chemical Process Research and Development, Second Edition
This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies. Fe...
