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Free-Radical-Induced DNA Damage and Its Repair
The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the ...
Verification, Validation and Testing in Software Engineering
Validation and verification is an area of software engineering that has been around since the early stages of program development, especially one of its more known areas: testing. Testing, the dynamic side of validation and verification (V&V), has been complemented with other, more formal techniques of software engineering, and so the static verification – traditional in formal methods – has been joined by model checking and other techniques. Verification, Validation and Testing in Software Engineering offers thorough coverage of many valuable formal and semiformal techniques of V&V. It explores, depicts, and provides examples of different applications in V&V that produce many areas of software development – including real-time applications – where V&V techniques are required.
NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces
NMR spectroscopy has found a wide range of applications in life sciences over recent decades. Providing a comprehensive amalgamation of the scattered knowledge of how to apply high-resolution NMR techniques to biomolecular systems, this book will break down the conventional stereotypes in the use of NMR for structural studies. The major focus is on novel approaches in NMR which deal with the functional interface of either protein-protein interactions or protein-lipid interactions. Bridging the gaps between structural and functional studies, the Editors believe a thorough compilation of these studies will open an entirely new dimension of understanding of crucial functional motifs. This in turn will be helpful for future applications into drug design or better understanding of systems. The book will appeal to NMR practitioners in industry and academia who are looking for a comprehensive understanding of the possibilities of applying high-resolution NMR spectroscopic techniques in probing biomolecular interactions.
The Truth About Heart Disease
You can prevent coronary heart disease in yourself, but you need to have the knowledge of the risk factors, the presenting symptoms and take early actions with aggressive and proper diagnostic testing. Start a prevention program for your heart health with The Truth About Heart Disease. In this book, Dr. Mark Houston provides you with scientific prevention and treatment programs to reduce your risk of coronary heart disease and myocardial infarction. These programs include optimal and proper nutrition, nutritional supplements, vitamins, antioxidants, anti-inflammatory agents, minerals, exercise, weight and body fat management, and other lifestyle changes. The Truth About Heart Disease is suitable for patients wanting to adopt preventive measures at home and anyone wanting to better manage their heart health. It will be of great value to all health care practitioners, cardiologists, and dietitians.
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An Intelligent Inspection Planning System for Prismatic Parts on CMMs
This book examines an intelligent system for the inspection planning of prismatic parts on coordinate measuring machines (CMMs). The content focuses on four main elements: the engineering ontology, the model of inspection planning for prismatic parts on CMMs, the optimisation model of the measuring path based on an ant-colony approach, and the model of probe configuration and setup planning based on a genetic algorithm. The model of inspection planning for CMMs developed here addresses inspection feature construction, the sampling strategy, probe accessibility analysis, automated collision-free operation, and probe path planning. The proposed model offers a novel approach to intelligent insp...
Real-Time Simulation Technologies: Principles, Methodologies, and Applications
Real-Time Simulation Technologies: Principles, Methodologies, and Applications is an edited compilation of work that explores fundamental concepts and basic techniques of real-time simulation for complex and diverse systems across a broad spectrum. Useful for both new entrants and experienced experts in the field, this book integrates coverage of detailed theory, acclaimed methodological approaches, entrenched technologies, and high-value applications of real-time simulation—all from the unique perspectives of renowned international contributors. Because it offers an accurate and otherwise unattainable assessment of how a system will behave over a particular time frame, real-time simulatio...
Statistics in Industry
This volume presents an exposition of topics in industrial statistics. It serves as a reference for researchers in industrial statistics/industrial engineering and a source of information for practicing statisticians/industrial engineers. A variety of topics in the areas of industrial process monitoring, industrial experimentation, industrial modelling and data analysis are covered and are authored by leading researchers or practitioners in the particular specialized topic. Targeting the audiences of researchers in academia as well as practitioners and consultants in industry, the book provides comprehensive accounts of the relevant topics. In addition, whenever applicable ample data analytic illustrations are provided with the help of real world data.
