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Frontiers in Anti-Infective Drug Discovery
“Frontiers in Anti-Infective Drug Discovery” is an Ebook series devoted to publishing the latest and the most important advances in Anti-Infective drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Infective drug design and discovery. Each volume is devoted to the major advances in Anti-Infective drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
Computational Methods in Systems Biology
This book constitutes the refereed proceedings of the 16th International Conference on Computational Methods in Systems Biology, CMSB 2018, held in BRNO, Czech Republic, in September 2018. The 15 full and 7 short papers presented together with 5 invited talks were carefully reviewed and selected from 46 submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology; parameter and model inference from experimental data; automated parameter and model synthesis; model integration and biological databases; multi-scale modeling and analysis methods; design, analysis, and verification methods for synthetic biology; methods for biomolecular computing and engineered molecular devices. Chapters 3, 9 and 10 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
New Developments in Liver Cirrhosis Research
The liver is a large organ that sits in the right upper abdomen, just under the right lung. It is one of the body's most "intelligent" organs in that it performs so many different functions at the same time. The liver makes proteins, eliminates waste material from the body, produces cholesterol, stores and releases glucose energy and metabolises many drugs used in medicine. It also produces bile that flows through bile ducts into the intestine where it helps to digest food. This organ also has the ability to regenerate itself if it is injured or partially removed. Cirrhosis is scarring of the liver that involves the formation of fibrous (scar) tissue associated with the destruction of the no...
Contrast Echocardiography in Clinical Practice
Echocardiography has now reached its maturity and plays a key role in the clinical assessment of cardiac function. However, its ability to assess myocardial perfusion remains a clinical challenge. Myocardial contrast echocardiography is a technique that uses microbubbles. These microbubbles remain entirely within the intravascular space and their presence in any myocardial region denotes the status of microvascular perfusion within that region. During the last few years, a large number of research studies have been dedicated to this topic. The latest developments in echocardiographic techniques and second-generation contrast agents allow for the potential assessment of myocardial perfusion and provide an accurate endocardial border delineation. In the present book, these new echocardiographic techniques dedicated to the assessment of myocardial perfusion are described in detail by experts from both sides of the Atlantic. Tips and tricks are included, explaining the basic concepts that are needed to understand and perform contrast echocardiography.
Lipid Disorders: A Multidisciplinary Approach, Clinics Collections, 1e, (Clinics Collections)
Clinics Collections: Lipid Disorders draws from Elsevier’s robust Clinics Review Articles database to provide multidisciplinary teams, including general practitioners, cardiologists, endocrinologists, pathologists, cardiologists, rheumatologists, and hepatologists, with practical clinical advice and insights on this highly prevalent condition and its comorbidities. Clinics Collections: Lipid Disorders guides readers on how to apply current primary research findings on lipid disorders to everyday practice to help overcome challenges and complications, keep up with new and improved treatment methods, and improve patient outcomes. • Areas of focus include lipids and biomarkers, lipids and p...
The Physiological Measurement Handbook
The Physiological Measurement Handbook presents an extensive range of topics that encompass the subject of measurement in all departments of medicine. The handbook describes the use of instruments and techniques for practical measurements required in medicine. It covers sensors, techniques, hardware, and software as well as information on processing systems, automatic data acquisition, reduction and analysis, and their incorporation for diagnosis. Suitable for both instrumentation designers and users, the handbook enables biomedical engineers, scientists, researchers, students, health care personnel, and those in the medical device industry to explore the different methods available for meas...
Cardiovascular Care in Patients With HIV
This book provides the most current overview of the evaluation and management of cardiovascular disease in people living with HIV/AIDS. The text assesses the risk factors associated with cardiovascular disease in HIV/AIDS patients and explores the most cutting edge ways to diagnose and treat the specific diseases that are most common for people living with HIV. This text takes a well-rounded, multidisciplinary approach that considers infectious disease and HIV specialists who may have little familiarity with the diagnosis and management of manifest CVD or risk factors as well as those in remote areas where providers may have little or no infrastructure to support optimal care for their patients. The text also serves cardiovascular specialists who may not have the expertise in HIV care to meet the unique needs of these patients. Cardiovascular Care for the Patient Living with HIV is the ultimate resource for not only all infectious disease and HIV specialists, but also for cardiologists, neurologists, vascular surgeons, general practitioners, nurse practitioners, physician’s assistants, and all other medical professionals who care for people living with HIV.
Sande's HIV/AIDS Medicine
Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care. - Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. - Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AI...
AIDS Bibliography
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Drug Delivery
An indispensable tool for those working at the front lines of new drug development Written for busy professionals at the forefront of new drug development, Drug Delivery gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments in such areas as combinatorial chemistry, proteomics, and genomics have revolutionized researchers' ability to rapidly identify and synthesize new pharmacological compounds. However, delivery-related properties remain a significant reason for clinical trial failures. Bringing together contributions by leading international experts, Drug Delivery covers the entire field in a...
