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The Black and Tans
The Black and Tans and Auxiliaries are the most notorious police forces in the history of the British Isles, and were the focus of bitter controversy. Based on extensive archival research, this is the first serious study of the forces and the part they played in the Irish War of Independence.
The Organic Chemistry of Drug Design and Drug Action
Drug discovery, design and development. Receptors. Enzymes. Enzyme inhibition and inactivation. DNA-interactive agents. Drug metabolism. Prodrugs and drug delivery systems.
Natural Products
Natural Products, Volume 61 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on Chemical evolution of natural product structure for drug discovery, Fungal Metabolites, Polypharmacology of Natural Products, Glycopeptide Antibiotics, and Natural products-based drug discovery for the CNS. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Annual Reports in Medicinal Chemistry serials Updated release includes the latest information on Natural Products
Vaccines for the Prevention of Cervical Cancer
Cervical cancer is the second most common form of cancer found in women, and it is responsible for more than a quarter of a million deaths worldwide each year. With approximately 70% of cervical cancers now known to be caused by two types of the human pailloma virus (HPV), there is great interest surrounding the approval of the first preventative vaccines for clinical use. Despite this excitement, many questions remain about how the new vaccines should best be implemented and how cervical cnancer screening will change following vaccination. Part of the Oxford Oncology Library series, this practical handbook provides an overview of the role of HPV in the pathology of cervical cancer and its current screening and management, the principles of immune control of HPV infection in cervical cancer, and the challenges of implementing HPV vaccines and future developments.
War and Revolution in the West of Ireland
The period 1913–22 witnessed extraordinary upheaval in Irish society. The Easter Rising of 1916 facilitated the emergence of new revolutionary forces and the eruption of guerrilla warfare. In Galway and elsewhere in the west, the new realities wrought by World War One saw the emergence of a younger generation of impatient revolutionaries. In 1916, Liam Mellows led his Irish Volunteers in a Rising in east Galway and up to 650 rebels took up defensive positions at Moyode Castle. From the western shores of Connemara to market towns such as Athenry, Tuam and Galway, local communities were subject to unprecedented use of terror by the Crown Forces. Meanwhile, conflict over land, an enduring gri...
The Black and Tans
This is the story of the Black and Tans and Auxiliaries, the most notorious police forces in the history of the British Isles. During the Irish War of Independence (1920-1), the British government recruited thousands of ex-soldiers to serve as constables in the Royal Irish Constabulary, the Black and Tans, while also raising a paramilitary raiding force of ex-officers - the Auxiliary Division. From the summer of 1920 to the summer of 1921, these forces became the focus of bitter controversy. As the struggle for Irish independence intensified, the police responded to ambushes and assassinations by the guerrillas with reprisals and extrajudicial killings. Prisoners and suspects were abused and...
Comprehensive Medicinal Chemistry II, Volume 3
This e-book comprises 8 volumes, with all chapter sections available as PDF or HTML, and includes bibliographical references and index.
Comprehensive Medicinal Chemistry III
Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
