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New experimental observations often require fresh concepts for their interpretation, and at times even changes of paradigms. This is the situation with the recent realization that circulating endothelial progenitor cells may have an important contribution to the maintenance and formation of new endothelium in adult organisms, in a surprisingly wide variety of situations. The classical paradigm of angiogenesis, centered on the notion of "sprouting" can hardly accommodate them. It was previously realized that it needs to be "stretched out" to include alternative mechanisms of microvascular development, such as intussusception and capillary fusion. However, a major debate where to reconsider th...
Suicide is an event that cannot be ignored, minimized, or left untreated. However, all too often mental health professionals and health care practitioners are unprepared to treat suicidal clients. This text offers the latest guidance to frontline professionals who will likely encounter such clients throughout their careers, and to educators teaching future clinicians. The book discusses how to react when clients reveal suicidal thoughts; the components of comprehensive suicide assessments; evidence-based treatments such as crisis intervention, cognitive behavior therapy, dialectical behavior therapy, and more; and ethical and legal issues that may arise. Case studies, exercises, quizzes, and other features make this a must-have reference for graduate level courses. Key topics: Risk and identification of suicidal behaviors across the lifespan (children, adolescents, adults, and the elderly) The links between suicidality and mental illness (psychotic disorders, mood disorders, and substance abuse) Suicide risk among special populations (military personnel, LGBTQ individuals, the homeless, and more) A model for crisis intervention with suicidal individuals
Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.
A Good Dying: Shaping Health Care for the Last Months of Life examines the critical issues of improving the quality of health care for end-of-life patients. You'll gain valuable suggestions and ideas for creating and maintaining policies that pertain to individuals with various diagnoses, family structures, and personal needs. A Good Dying provides methods and examples that will help managers of health care focus on the needs of patients and make their last days as comfortable as possible. Emphasizing the need for further education of health care professionals and the need for additional research, A Good Dying offers possible solutions to the many barriers of improving conditions for the dyi...
Do real stem cells and stem cell lineages exist in lower organisms? Can stem cells from one organism parasitize the soma and/or the germ line of conspecifics? Can differentiated cells in marine organisms be re-programmed to regenerate tissues, organs and appendages through novel de-differentiation, transdifferentiation, or re-differentiation processes, leading to virtually all three germ layers, including the germline? The positive answers to above questions open a new avenue in stem cell research: the biology of stem cells in marine organisms. It is therefore unfortunate that while the literature on stem cell from terrestrial organisms is rich and expanding at an exponential rate, investiga...
Established for fifteen years as the standard work in the field, Melvin Lewis's Child and Adolescent Psychiatry: A Comprehensive Textbook is now in its Fourth Edition. Under the editorial direction of Andrés Martin and Fred R. Volkmar—two of Dr. Lewis's colleagues at the world-renowned Yale Child Study Center—this classic text emphasizes the relationship between basic science and clinical research and integrates scientific principles with the realities of drug interactions. This edition has been reorganized into a more compact, clinically relevant book and completely updated, with two-thirds new contributing authors. The new structure incorporates economics, diversity, and a heavy focus on evidence-based practice. Numerous new chapters include genetics, research methodology and statistics, and the continuum of care and location-specific interventions. A companion Website provides instant access to the complete, fully searchable text.
News about this title: — Author Marty Weissman has been awarded a Guggenheim Fellowship for 2020. (Learn more here.) — Selected as a 2018 CHOICE Outstanding Academic Title — 2018 PROSE Awards Honorable Mention An Illustrated Theory of Numbers gives a comprehensive introduction to number theory, with complete proofs, worked examples, and exercises. Its exposition reflects the most recent scholarship in mathematics and its history. Almost 500 sharp illustrations accompany elegant proofs, from prime decomposition through quadratic reciprocity. Geometric and dynamical arguments provide new insights, and allow for a rigorous approach with less algebraic manipulation. The final chapters cont...
The aim of this book is not to encourage defensive medical practice, but to help provide better, optimum care to patients and to be forth right and honest to our dear customers about our inevitable mistakes. This book will focus on clinical issues facing physicians in different settings (which can lead to malpractice), and the best approach to use to avoid litigations, and practice good medicine.
The use of Information and Communication Technologies (ICT) to deliver psychological services has been emerging as an effective way of increasing individual access to mental health promotion, prevention, and treatment. This Special Issue brings together different contributions focusing on the acceptability and feasibility, (cost-)effectiveness, potentialities, and limitations of ICT-based psychological services for mental health promotion, prevention, and treatment. In each paper, the implications for the implementation of ICT tools in different settings (e.g., primary care services) and for future research are discussed.