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Protein Tyrosine Phosphatases
This second edition volume expands on the previous edition with discussions on the latest advancements in protein tyrosine phosphatases (PTP) research used to investigate these essential enzymes and new inhibitors. The new techniques covered in the chapters of this book include studying enzymes in vitro, in cells, and in animal models through proteomics, genomics, and structural biology. Furthermore, new advances in pharmacology and drug design have contributed to the developing novel therapeutics that target PTPs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Protein Tyrosine Phosphatases: Methods and Protocols, Second Edition is a valuable resource for both experienced and novel researchers in this field, and will lead to discoveries and accelerated progress in the field of PTP, signal transduction, and drug development.
A Time to Die
Behind monastery walls, men of God spend their lives preparing for the passage of death. Best-selling French author Nicolas Diat set out to find what their deaths can reveal about the greatest mystery faced by everyone—the end of life. How to die? How to respond to our fear of death? To answer these and other questions, Diat travelled to eight European monasteries including Solesmes Abbey and the Grande Chartreuse. Through extraordinary interviews with monks, he learned that their death experiences are varied and unique, with elements of peace, pain, humility, sorrow, and joy. These monks have the same fears, torments, and sorrows as everyone else, Diat discovered. What is exemplary about them is their humility and simplicity. When death approaches, and its hand reveals its strength, they are like happy and naïve children who wait with impatience to open a gift. They have complete confidence in the mercy of God.
Departement du Jura
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The Chemistry of the Actinide and Transactinide Elements (3rd ed., Volumes 1-5)
The Chemistry of the Actinide and Transactinide Elements is a contemporary and definitive compilation of chemical properties of all of the actinide elements, especially of the technologically important elements uranium and plutonium, as well as the transactinide elements. In addition to the comprehensive treatment of the chemical properties of each element, ion, and compound from atomic number 89 (actinium) through to 109 (meitnerium), this multi-volume work has specialized and definitive chapters on electronic theory, optical and laser fluorescence spectroscopy, X-ray absorption spectroscopy, organoactinide chemistry, thermodynamics, magnetic properties, the metals, coordination chemistry, ...
The Chemistry of the Actinide and Transactinide Elements (Set Vol.1-6)
The fourth edition of "The Chemistry of the Actinide and Transactinide Elements" comprises all chapters in volumes 1 through 5 of the third edition (published in 2006) plus a new volume 6. To remain consistent with the plan of the first edition, “ ... to provide a comprehensive and uniform treatment of the chemistry of the actinide [and transactinide] elements for both the nuclear technologist and the inorganic and physical chemist,” and to be consistent with the maturity of the field, the fourth edition is organized in three parts. The first group of chapters follows the format of the first and second editions with chapters on individual elements or groups of elements that describe and ...
Un temps pour mourir
Comment mourir ? Comment répondre à nos peurs ? Derrière les murs des monastères, les hommes de Dieu passent leur existence à préparer le grand passage. Peuvent-ils nous aider à comprendre la souffrance, la maladie, la peine et la solitude des derniers instants ? De Cîteaux à Lagrasse, de la Grande-Chartreuse à Solesmes, Nicolas Diat a recueilli les confidences de moines sur la fin de leurs vies. Au fil d’entretiens exceptionnels menés dans huit monastères, au plus près des « fils du silence », nous comprenons que leurs morts ne se ressemblent pas : il y en a de simples, d’heureuses, de belles et de lumineuses, des agonies lentes ou douloureuses. L’auteur raconte le calv...
Le grand bonheur
« Venez, et voyez Fontgombault. Oh, il ne se passera rien de spectaculaire. Mais nos cœurs se réchaufferont. Une petite grâce mystérieuse soufflera. Nous regarderons la lumière traverser l’abbatiale, les arbres des vergers danser dans le vent, les moines marcher au loin, vers les coteaux. Les notes grégoriennes s’élèveront dans les hauteurs mystiques. Nous serons des enfants subjugués par les processions splendides. Nous resterons silencieux. Et nous verrons le beau, le merveilleux, le doux sourire des moines. » C’est par ces mots que Nicolas Diat ouvre Le Grand Bonheur. Ce livre est une invitation à la joie, une invitation à nous faire découvrir la vie des moines pour no...
