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Cell Stress Proteins
This book surveys the current knowledge concerning the expression and function of stress proteins in different organisms, ranging from prokaryotes to humans. It provides an overview of the diversity and complex evolutionary history of cell stress proteins and describes their function and expression in different eukaryote models. The book will appeal to researchers and scientists in biochemistry, cell biology, microbiology, immunology, and genetics.
The Tools of Science
This book aims to provide useful tips for the understanding of scientific research processes and practical advice for people engaged in this field. It is a reflection of the author's more than 40 years of experience in medical and cancer research, and is written in a colloquial style to reach not only the young audience who are considering devoting their lives to biomedical research, but also to those who are already engaged in this field. The author emphasizes the unique traits and qualifications required for performing scientific research and also describes the different modalities which can be performed in our actual scientific environment. There are numerous practical advices in this book, such as guidelines on writing a grant proposal and the first peer-reviewed manuscript, the selection criteria of the training laboratory and mentors, as well as keeping records of experimental data. The author also provides his insight on the personal inner drive and motivation critical for conducting scientific research, as well as the importance of working on a problem without losing the human perspective of this specific and unique human endeavor.
Drug Resistance in Oncology
This timely new reference integrates the latest clinical results and laboratory studies on the resistance of specific cancers to chemotherapeutic drugs-covering drug resistance in lung, breast, ovary, and colon cancer as well as hematological malignancies.
Small Stress Proteins
This book gives a comprehensive survey of the current knowledge of the expression and function of small stress proteins (sHsps) in different organisms, from prokaryotes to humans. It provides an overview of the diversity and complex evolutionary history of sHsps and describes their function and expression in different eukaryote models. Additional chapters discuss the role of sHsps in pathological conditions and gene therapy approaches towards a control of sHsp expression levels.
Frontiers in Clinical Drug Research - Anti-Cancer Agents
Frontiers in Clinical Drug Research - Anti-Cancer Agents should prove to be a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field. The chapters featured in each volume are written by leading experts in oncology and clinical pharmacology. The eBook series is essential reading for all scientists involved in clinical drug research who wish to keep abreast of rapid and important developments in the development of anti-cancer agents. The contents of this volume include reviews on dendrimers for anti-cancer drug delivery, treatment methods for advanced cutaneous squamous cell carcinoma, targeting heat shock proteins for cancer treatment, Bayesian systems for optimizing treatment protocols in oncology and much more.
Role of the Transcriptome in Breast Cancer Prevention
This book will provide the latest advances in molecular and cellular biology for establishing the foundation of a complete understanding of the mechanisms of breast differentiation leading to cancer prevention. The authors are based on the epidemiological evidence indicating that early first full term pregnancy is a protective factor in human against breast cancer and they have used this paradigm and developed experimental systems in both in vivo and in vitro that have demonstrated mechanistically how the differentiation at the organ and cellular level takes place. This knowledge has provided the blueprint for developing better understanding of the basis of cancer prevention. The transcripto...
Femtosecond Technology for Technical and Medical Applications
There is no doubt that the advent of immunocytochemical techniques, by enhancing our ability to detect specific cell products or markers, has opened new avenues in the understanding of human diseases, and in our ability to perform better diagnosis in surgical pathology. The rapid development of this field has resulted in thousands of publications in the literature regarding immunocytochemistry in diagnostic pathology. This explosion of knowledge makes necessary publications summarizing what are the main markers available and how they can be used in the diagnosis of tumors. The need of a more organized and structured knowledge was evident during the workshop in Immunocytochemistry of Tumor Diagnosis that took place in the City of Detroit an October 1984. This book is the result of that workshop in which 22 chapters are focusing an the main subject of differential diagnosis of tumors. Jose Russo, M.D. Editor xiii ACKNOWLEDGEMENTS I wish to thank my many associates at the Michigan Cancer Foundation for their help in the preparation of this manuscript. I give thanks to Dr.
Cancer Research
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