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Osteogenesis and Bone Regeneration
Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis.
Dental Stem Cells
This book explores Dental Stem Cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine. The first seven chapters delve into basic DSC properties, vital signaling pathways involved in differentiation, pluripotency, iPS cell development from DSCs, and genetic engineering approaches of DSCs in accordance with the current literature. A comprehensive review of possible clinical applications and in vitro/in vivo studies follows, illustrating the future of DSC research for in the tissue engineering field. The text also discusses the political, ethical, social, and legal ramifications of the use of dental stem cells. Expertly authored and drawing from a multitude of international perspectives, Dental Stem Cells is an invaluable addition to Springer’s Stem Cell Biology and Regenerative Medicine series. It is essential reading for advanced graduate students, basic researchers, and clinical investigators in the fields of stem cell therapy, biological sciences of dentistry, and regenerative medicine.
Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery
Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therap...
Crónicas de una masacre
Distrito Federal, México, año 1998. Antonio es un joven que dedica sus días a trabajar en el restaurante Minna Jima ubicado en plaza Los Arcos. Franco es un estudiante de último año de preparatoria con esquizofrenia que constantemente sufre las burlas de sus compañeros. Ambos parecen vivir en lados opuestos del tablero, pero Franco y Antonio no son tan distintos, ellos han decidido ir más allá. Antonio, empujado por sus más bajos instintos, se ha convertido en asesino en serie. Y Franco ha hecho un plan para vengarse de todos aquellos que lo creyeron débil. La combinación de estas dos personalidades desencadenará la más brutal masacre de la que se haya escuchado en México.
Composición social del Estado Plurinacional
Composición social del Estado Plurinacional investiga la transformación del perfil social de los servidores públicos en Bolivia brindando evidencia empírica sobre los avances en la descolonización del Estado. El estudio muestra que el acceso a la burocracia se ha democratizado sin perder capacidades ni institucionalidad. Los nuevos servidores públicos son más jóvenes, hay más indígenas y mujeres que en el pasado y tienen mejores niveles educativos, ocupacionales y de ingreso que sus padres. Sin embargo, estos cambios no escinden, al contrario, fortalecen su identidad étnica, potenciando la subjetividad de quienes tienen la responsabilidad diaria de construir el Estado Plurinacional.
LA ESCRITORA
Esta vida está llena de obstáculos. De momentos de odio y rabia. De desamores. De lágrimas de desesperación. De situaciones amargas. De desilusiones e hipocresías. Pero también de valiosas lecciones. De instantes de risa y camarería. De amores. De alegres llantos. De dulces segundos. De esperanza y claridad. Y de sexo... ¡Mucho sexo! Adéntrate en un mundo donde todos estos elementos se conjugan en una perfecta armonía. En una dulce sincronía. En un baile erótico, sensual. Donde los gemidos, gruñidos y gritos son los personajes principales que te llevarán por el camino que todos transitamos. Únete a estos seres en su lucha continua por alcanzar sus objetivos. Sus metas. Sus sue...
The Case for Marriage
A groundbreaking look at marriage, one of the most basic and universal of all human institutions, which reveals the emotional, physical, economic, and sexual benefits that marriage brings to individuals and society as a whole. The Case for Marriage is a critically important intervention in the national debate about the future of family. Based on the authoritative research of family sociologist Linda J. Waite, journalist Maggie Gallagher, and a number of other scholars, this book’s findings dramatically contradict the anti-marriage myths that have become the common sense of most Americans. Today a broad consensus holds that marriage is a bad deal for women, that divorce is better for childr...
Self Portrait in Green
'NDiaye is a hypnotic storyteller with an unflinching understanding of the rock-bottom reality of most people's life.' New York Times ' One of France's most exciting prose stylists.' The Guardian. Obsessed by her encounters with the mysterious green women, and haunted by the Garonne River, a nameless narrator seeks them out in La Roele, Paris, Marseille, and Ouagadougou. Each encounter reveals different aspects of the women; real or imagined, dead or alive, seductive or suicidal, driving the narrator deeper into her obsession, in this unsettling exploration of identity, memory and paranoia. Self Portrait in Green is the multi-prize winning, Marie NDiaye's brilliant subversion of the memoir. Written in diary entries, with lyrical prose and dreamlike imagery, we start with and return to the river, which mirrors the narrative by posing more questions than it answers.
