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Structure And Action Of Molecular Chaperones: Machines That Assist Protein Folding In The Cell
This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, which provide essential kinetic assistance to processes of protein folding and unfolding in the cell. Ranging from multisubunit ring-shaped chaperonin and Hsp100 machines that use their central cavities to bind and compartmentalize action on proteins, to machines that use other topologies of recognition — binding cellular proteins in an archway or at the surface of a 'clamp' or at the surface of a globular assembly — the structures show us the ways and means the cell has devised to assist its major effectors, proteins, to reach and maintain their unique active forms, as well as, when required, to disrupt protein structure in order to remodel or degrade. Each type of chaperone is beautifully illustrated by X-ray and EM structure determinations at near- atomic level resolution and described by a leader in the study of the respective family. The beauty of what Mother Nature has devised to accomplish essential assisting actions for proteins in vivo is fully appreciable.
Michigan History
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A Way to Garden
“A Way to Garden prods us toward that ineffable place where we feel we belong; it’s a guide to living both in and out of the garden.” —The New York Times Book Review For Margaret Roach, gardening is more than a hobby, it’s a calling. Her unique approach, which she calls “horticultural how-to and woo-woo,” is a blend of vital information you need to memorize and intuitive steps you must simply feel and surrender to. In A Way to Garden, Roach imparts decades of garden wisdom on seasonal gardening, ornamental plants, vegetable gardening, design, gardening for wildlife, organic practices, and much more. She also challenges gardeners to think beyond their garden borders and to consider the ways gardening can enrich the world. Brimming with beautiful photographs of Roach’s own garden, A Way to Garden is practical, inspiring, and a must-have for every passionate gardener.
Newsweek
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Saturday Review
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Congressional Record
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Nonlinear Transistor Model Parameter Extraction Techniques
Achieve accurate and reliable parameter extraction using this complete survey of state-of-the-art techniques and methods. A team of experts from industry and academia provides you with insights into a range of key topics, including parasitics, intrinsic extraction, statistics, extraction uncertainty, nonlinear and DC parameters, self-heating and traps, noise, and package effects. Learn how similar approaches to parameter extraction can be applied to different technologies. A variety of real-world industrial examples and measurement results show you how the theories and methods presented can be used in practice. Whether you use transistor models for evaluation of device processing and you need to understand the methods behind the models you use, or you want to develop models for existing and new device types, this is your complete guide to parameter extraction.
Modulating Prokaryotic Lifestyle by DNA-Binding Proteins
The Overview of the Topic was the following: "One of the most active areas of research in molecular microbiology has been the study of how bacteria modulate their genetic activity and its consequences. The prokaryotic world has gained a lot of interest. In addition to the above, the invention is based on the subject-matter of the present invention, which is incorporated herein by reference in its entirety. All of these processes are fundamental to the operation of a genetic entity and condition their lifestyle. Further, the discoveries in the bacterial world have been of ample use in eukaryotes. [Article in German] Hansen, Hansen, H. (2003). In addition to the fundamental interest in underst...
