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Teaching America
In Teaching America, more than 20 leading thinkers sound the alarm over a crisis in citizenship—and lay out a powerful agenda for reform. The book’s unprecedented roster of authors includes Justice Sandra Day O’Connor, Senator Jon Kyl, Senator Bob Graham, Secretary Rod Paige, Alan Dershowitz, Juan Williams, Glenn Reynolds, Michael Kazin, Frederick Hess, Andrew Rotherham, Mike Feinberg, Seth Andrew, Mark Bauerlein and more. Their message: To remain America, our country has to give its kids a civic identity, an understanding of our constitutional system, and some appreciation of the amazing achievements of American self-government. But we are failing. Young Americans know little about the Bill of Rights, the democratic process, or the civil rights movement. Three of every four high school seniors aren’t proficient in civics, nine of ten can’t cut it in U.S. history, and the problem is only aggravated by universities' disregard for civic education. Such civic illiteracy weakens our common culture, disenfranchises would-be voters, and helps poison our politics.
National Security Policy Proceedings: Spring 2010
The inaugural volume of the Center for Security Policy's National Security Policy Proceedings includes transcripts of remarks by Douglas Feith, David Satter, Walid Phares, Allen West and Paul Rosenzwieg. Book reviews by Gordon Chang, Paula DeSutter, Robert Reilly and Christine Brim. Introduction by Frank Gaffney.
What's A Parent to Do?
Each year over a million newly-minted high school graduates enroll in four-year colleges and universities across the country. They do so often after a lengthy and almost always stressful selection process. Faced with growing evidence of declining standards, rising political correctness and spiraling costs, families feel more powerless than ever before – and question whether a college degree is really the key to the American dream. What is a parent to do? This book provides an answer. Higher education expert Anne Neal offers families a concise guide to finding the right college. Rejecting the notion that reputation is everything, this guide offers insightful chapters on curricula and teaching, campus and dorm life, freedom of thought and speech, and affordability – issues that are more and more in the news. Families are given a handy checklist of questions designed to help them zero in on key issues of quality and cost to ensure a college program that will provide the skills and knowledge needed for success after graduation.
Democracy
Historian David Moss adapts the case study method made famous by Harvard Business School to revitalize our conversations about governance and democracy and show how the United States has often thrived on political conflict. These 19 cases ask us to weigh choices and consequences, wrestle with momentous decisions, and come to our own conclusions.
Precision Cancer Therapies, Volume 1
A Thorough Compilation of the Many Scientific Breakthroughs in the Ongoing Development of Precision Cancer Therapies Related to Lymphoma Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice focuses on lymphoma, an area which has seen a remarkable number of breakthroughs in the ongoing development of precision cancer therapies. Each section on a specific biology or class of drugs has an introductory chapter written by an authority in the field, exclusively focused on the science and its relevance to cancer biology. This approach addresses the need for scientists, physicians, and the private sector to understand the broader context of the extrao...
Rethinking Cancer
Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical...
Neuroblastoma
Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.
The Peripheral T-Cell Lymphomas
THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Pe...
