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Necrotizing Enterocolitis
This is the first textbook devoted entirely to understanding and treating necrotizing enterocolitis (NEC), one of the leading causes of death and disability in premature infants. NEC continues to occur in neonatal units across the world, and the overall mortality has remained stubbornly high since its first description decades ago. Despite significant research into NEC, and a greater understanding of its underlying causes, there is no single source of information to which the care team can turn for guidance. This book fills that important gap in clinical care. In selecting the topics for this inaugural textbook, three guiding principles have been followed. First, to include chapters that pro...
Phagocytosis: The Host
An accompanying volume (Volume 6) in this series presents strategies of cellular invasion from the viewpoint of the microbe.This filed of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research, and brings together cell biologists, microbiologists and immunologists with disparate interests. However, there is a certain unity, even repetition of key themes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular paratism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage, and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pathogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is cytogenes, share common strategies in invasion and intercellular spread.
Cytokines in Severe Sepsis and Septic Shock
t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word "sepsis" derives from the Greek meaning decay or rottenness. Tradition ally this term has been used to describe the process of infection accompanied by the host's systemic inflammatory response. Based on that understanding, previous clin ical studies have been designed to include only patients with positive blood cultures [1, 2]. However, the frequent occurrence of a septic response without the demon stration of microorganisms in the circulation has led to a new definition and under standing of sepsis, mainly as the systemic response of the host to an often unde tec...
Fundamentals of Pediatric Surgery
The first two editions of Fundamentals of Pediatric Surgery (2011, 2017) were meant to be comprehensive, state-of-the-art, and practical. The 3rd edition builds on this commitment to such time-honored principles with a text that is even more wide-ranging in its content. It has a deeper commitment to relying on the most current scientific evidence, provides additional study materials to aid in comprehension of concepts and for more effective preparation for oral and written examinations, and be accessible through a variety of multimedia platforms for busy surgeons who have less and less time to sit and read a text but who need to understand this important material while on call, on the go, or...
Surgical Research
A unique reference manual for academic surgeons, this book discusses every facet of surgical research. From getting grant money to choosing a topic, reviewing the literature, planning and conducting research, and reporting results.
Current Surgical Therapy E-Book
An ideal resource for written, oral, and recertifying board study, as well as an excellent reference for everyday clinical practice, Current Surgical Therapy, 13th Edition, provides trusted, authoritative advice on today's best treatment and management options for general surgery. Residents and practitioners alike appreciate the consistent, highly formatted approach to each topic, as well as the practical, hands-on advice on selecting and implementing current surgical approaches from today's preeminent general surgeons. - Provides thoroughly updated information throughout all 263 chapters, including focused revisions to the most in-demand topics such as management of rectal cancer, inguinal ...
Success in Academic Surgery: Basic Science
This updated volume provides the foundation for starting a basic science research career as an academic surgeon. Taking a practical approach, the book covers the suggested timeline for the initial academic appointment, including how to setup and fund the laboratory and identifying appropriate scientific mentors and lab personnel. It also describes the application of basic and advanced research techniques, including animal models, flow cytometry, gene editing, tissue engineering, and microbiome analysis. Success in Academic Surgery: Basic Science aims to give guidance on the application of basic and advanced techniques in surgical research. This book is relevant to senior residents and fellows approaching their first academic appointment, as well as more senior investigators interested in expanding their research horizons.
Intestinal Failure,An Issue of Gastroenterology Clinics of North America E- Book
For this important and unique issue of Gastroenterology Clinics, Consulting Editor Dr. Alan Buchman decided to serve as co-Guest Editor with Dr. David Hackam to provide a “bench to bedside look at intestinal failure. Authors have contributed reviews on the status of the science behind artificial organs while emphasizing how to clinically prepare for intestinal failure. Articles are devoted to the following topics: Initial Evaluation and Care of the Patient with New Onset Intestinal Failure; Getting the Patient Ready for Home Parenteral Nutrition; Pediatric Intestinal Failure: Etiology and Management; Predictors of Intestinal Adaptation in Children; Management of the Patient with Chronic In...
