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Pediatric Epilepsy
The extensively updated third edition of Pediatric Epilepsy: Diagnosis and Therapy continues to be the definitive volume on the diagnosis, treatment, classification, and management of the childhood epilepsies. Written by nearly 100 international leaders in the field, this new edition progresses logically with major sections on the basic mechanisms of the disease, classification, epidemiology, etiology, diagnosis, and age-related syndromes of epilepsy. The core of the new third edition is its completely updated section on antiepileptic drugs, including an in-depth discussion of dosage considerations, drug toxicity, teratogenicity, and drug interactions, with recommendations for optimal combin...
Innovaciones tecnológicas para la enseñanza superior: contribuciones y resultados
La utilización de tecnologías educativas en el ámbito docente ha experimentado un crecimiento significativo en los últimos años, sobre todo tras la pandemia sufrida por el virus COVID-19 y el necesario confinamiento al que nos vimos abocados. Los avances tecnológicos y la accesibilidad a Internet han permitido que tanto los docentes como los estudiantes aprovechen diversas herramientas y recursos digitales para mejorar el proceso de enseñanza y aprendizaje. Una de las claves para una implementación exitosa de las innovaciones docentes con tecnologías en la docencia es asegurarse de que se utilicen de manera efectiva, se adapten a las necesidades de los estudiantes y se integren de m...
Techniques to Investigate Mitochondrial Function in Neurons
This volume describes a broad spectrum of experimental approaches for investigating structure, function, and transport of neuronal mitochondria in health and disease. Most of these approaches were only recently developed and range from electron tomography-based 3D reconstruction of mitochondrial cristae to patch clamp recording from mitochondria in intact neurons. The chapters in this book cover topics such as mitochondrial proteomics, fluorescence lifetime imaging, respirometry and mitophagy, as well as optical approaches based on the use of genetically engineered fluorescent sensors for monitoring synaptic ATP and axonal ROS generation, mitochondrial Ca2+ cycling and pH changes, and mitoch...
Innovative Medicine
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is ...
Ryan's Retina E-Book
Through six outstanding and award-winning editions, Ryan's Retina has offered unsurpassed coverage of this complex subspecialty—everything from basic science through the latest research, therapeutics, technology, and surgical techniques. The fully revised 7th Edition, edited by Drs. SriniVas R. Sadda, Andrew P. Schachat, Charles P. Wilkinson, David R. Hinton, Peter Wiedemann, K. Bailey Freund, and David Sarraf, continues the tradition of excellence, balancing the latest scientific research and clinical correlations and covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. More than 300 global contributors share their kn...
Mitochondrial Translocases Part B
Mitochondrial Translocases Part B series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an internation. - Provides the latest information on biological research - Offers outstanding and original reviews on a range of biological research topics - Serves as an indispensable reference for researchers and students alike
Bioenergetics
Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergeti...
The Dynamic Nature of Mitochondria
Mitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature, controlling life at multiple levels. Mitochondria rule energy conversion, adapt cells well to changing stress and nutrient conditions, and regulate many cellular processes including immunity. The dynamic nature of mitochondria occurs at an intramitochondrial level but also includes its ability to interact with other organelles and to modulate multiple signalling pathways. It is thus not surprising that alterations or inabilities to ensure this dynamic behaviour is...
