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Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science. Please note that Garland Science flashcards are no longer available for this text. However, the solutions can be obtained through our Support Material Hub link below, but should only be requested by instructors who have adopted the book on their course.
Superelectrophiles and Their Chemistry contains, for the first-time, a discussion of the basics of this emerging field of organic chemistry, alongside tools to help the reader apply the chemistry. Specific tools include an evaluation of the ways to increase the strength of electrophiles, the classification of superelectrophiles, the solvation issues, a review of methods for studying superelectrophilicity, with details of the superelectrophiles that have been identified and studied. Additional information includes substituent effects in activation of superelectrophiles, and solvation in chemical reactions, as well as an insightful look into future applications.
Computational Quantum Chemistry presents computational electronic structure theory as practised in terms of ab initio waveform methods and density functional approaches. Getting a full grasp of the field can often prove difficult, since essential topics fall outside of the scope of conventional chemistry education. This professional reference book provides a comprehensive introduction to the field. Postgraduate students and experienced researchers alike will appreciate Joseph McDouall's engaging writing style. The book is divided into five chapters, each providing a major aspect of the field. Electronic structure methods, the computation of molecular properties, methods for analysing the output from computations and the importance of relativistic effects on molecular properties are also discussed. Links to the websites of widely used software packages are provided so that the reader can gain first hand experience of using the techniques described in the book.
Also included is a thorough review of the molecular genetics of both trichothecene and fumonisin biosynthesis, presenting more than 15 years of molecular biological research in an accessible form. Part one then reviews the natural occurrence and toxicity of agriculturally important mycotoxins, with historical case studies of suspected mycotoxicoses in humans and animals. These chapters also contain updates on the molecular genetics of additional mycotoxins and the importance of mycotoxins in plant diseases. This useful reference presents concise descriptions of mycotoxin-producing Fusarium species, as defined by the most recent concepts of fungal species biology and evolution. Each species' report includes a risk assessment based on its mycotoxin profile, occurrence in food and feed crops, and association with human and animal mycotoxicoses. Data on species distribution, mycotoxin profiles, and animal toxicity facilitate risk assessment for food and feed safety.
The story that unfolds in this work manifests the pursuit of one of the many historical mysteries that plague the early history of people of African descent in New York State - a mass migration of thousands of African descendants to Washington County, New York at the turn of the 19th century. The impact of this de-valued history and its absence from the historical record has distorted the recollection and remembrance of people of African descent in New York, whose ancestors were trapped in the confinement of enslavement and second-class citizenship. This unrecorded migration transpired while New York was beginning to alter its highly profitable economic system from an enslavement-based econo...
Written by a master teacher, Advanced Organic Chemistry presents a clear, concise, and complete overview of the subject that is ideal for both advanced undergraduate and graduate courses. In contrast with many other books, this volume is a true textbook, not a reference book. FEATURES * Uses a unique method of categorizing organic reactions that is based on reactivity principles rather than mechanism or functional group, enabling students to see reactivity patterns in superficially widely disparate systems * Emphasizes fundamental physical organic concepts that reinforce themes, giving students the foundation to understand both mechanisms and synthesis * Covers asymmetric methodologies, a to...
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.