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This third volume provides comprehensive protocols on pre-analytical, analytical, plasma, and serum proteomics. New and updated chapters are divided into nine sections, detailing blood processing and handling strategies, discovery- and targeted-based mass spectrometry, including workflows to aid in discovery and targeted data analysis, in addition to software and bioinformatics for the plasma proteome. This edition further integrates emerging areas in the development of technologies for plasma proteomics and assay platforms in biomarker discovery and translational proteomics, enrichment and detection strategies to understand the plasma proteome, and peptide, lipid and metabolite targeted ass...
Blood science has become a cornerstone of multiple disciplines. This book, contributed to by leading experts in the field, provides a comprehensive resource of protocols for areas, pre-analytical through to analytical, of plasma and serum proteomics.
This work covers important and neglected ground—environmental language theory. Gilcrest poses two overarching questions: To what extent does contemporary nature poetry represent a recapitulation of familiar poetics? And, to what extent does contemporary nature poetry engage a poetics that stakes out new territory? He addresses these questions with important thinkers, especially Kenneth Burke, and considers such poets as Frost, Kunitz, Heaney, Ammons, Cardenal, and Rich.
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Topic Editor RL is a patent inventor on exosome-related patents, PCT/AU2017/050821 and PCT/AU2016/050468. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
For decades we have known that the overgrowth, hardening and scarring of tissues (so-called fibrosis) represents the final common pathway and best histological predictor of disease progression in most organs. Fibrosis is the culmination of both excess extracellular matrix deposition due to ongoing or severe injury, and a failure to regenerate. An inadequate wound repair process ultimately results in organ failure through a loss of function, and is therefore a major cause of morbidity and mortality in disease affecting both multiple and individual organs. Whilst the pathology of fibrosis and its significance are well understood, until recently we have known little about its molecular regulati...
In this book—one of the first ecocritical explorations of Irish literature—Alison Lacivita defies the popular view of James Joyce as a thoroughly urban writer by bringing to light his consistent engagement with nature. Using genetic criticism to investigate Joyce’s source texts, notebooks, and proofs, Lacivita shows how Joyce developed ecological themes in Finnegans Wake over successive drafts. Making apparent a love of growing things and a lively connection with the natural world across his texts, Lacivita’s approach reveals Joyce’s keen attention to the Irish landscape, meteorology, urban planning, Dublin’s ecology, the exploitation of nature, and fertility and reproduction. Alison Lacivita unearths a vital quality of Joyce’s work that has largely gone undetected, decisively aligning ecocriticism with both modernism and Irish studies.
The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.
Explores the ways in which American poetry has documented and sometimes helped propel the literary and cultural revolutions of the past sixty-five years.