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For this second edition of their much praised Cytochrome P450, the editors have collected accounts of the essential core techniques that use the latest methodologies for the investigation of P450s. Highlights include protocols for spectral analysis and purification of P450s, enzymatic assays of P450s and flavin-containing monooxygenases (FMOs), expression of P450s and FMOs in heterologous systems, and the production and use of antipeptide antibodies. Additional chapters contain readily reproducible techniques for the transfection of hepatocytes for gene regulation studies, P450 reporter gene assays, in situ hybridization, and analysis of genetic polymorphisms. Although the emphasis is on P450s of mammalian origin, many of the readily reproducible methods described are suitable for P450s from any source.
2006 National Jewish Book Award, Modern Jewish Thought Long the object of curiosity, admiration, and gossip, rabbis' wives have rarely been viewed seriously as American Jewish religious and communal leaders. We know a great deal about the important role played by rabbis in building American Jewish life in this country, but not much about the role that their wives played. The Rabbi’s Wife redresses that imbalance by highlighting the unique contributions of rebbetzins to the development of American Jewry. Tracing the careers of rebbetzins from the beginning of the twentieth century until the present, Shuly Rubin Schwartz chronicles the evolution of the role from a few individual rabbis' wives who emerged as leaders to a cohort who worked together on behalf of American Judaism. The Rabbi’s Wife reveals the ways these women succeeded in both building crucial leadership roles for themselves and becoming an important force in shaping Jewish life in America.
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New portrayals of the religious lives of American Jewish women from colonial times to the present.
Upon his arrival in Hollywood, Alfred Hitchcock began work on his first American film, an adaptation of Daphne du Maurier’s best-selling novel. Produced by David O. Selznick and featuring compelling performances by Laurence Olivier, Joan Fontaine, and Judith Anderson, Rebecca became one of Hitchcock’s most successful films. It was nominated for eleven Academy Awards and received the Oscar for Best Picture, the only Hitchcock work to be so honored. Without question, one of the reasons for the film’s success is its ninety minutes of dramatic musical underscoring by Franz Waxman. In Franz Waxman’s Rebecca: A Film Score Guide, David Neumeyer and Nathan Platte situate the score for this c...
In Hidden Depths, Robin Waterfield explores the fascinating world of hypnosis, tracing the history of this often misunderstood craft beginning with a passage in the book of Genesis, and continuing through his own personal experiences today. Waterfield uses the history and controversy surrounding the practice of hypnosis to gain insight into our behavior and psychology, and considers how hypnotic techniques have been absorbed into society through advertising, media and popular culture.
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This book constitutes the refereed proceedings of the 10th International Conference on Simulation of Adaptive Behavior, SAB 2008, held in Osaka, Japan in July 2008. The 30 revised full papers and 21 revised poster papers presented were carefully reviewed and selected from 110 submissions. The papers are organized in topical sections on the animat approach to adaptive behaviour, evolution, navigation and internal world models, perception and control, learning and adaptation, cognition, emotion and behaviour, collective and social behaviours, adaptive behaviour in language and communication, and applied adaptive behaviour.
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