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Atlas on the Human Testis
Atlas on the Human Testis: Normal Morphology and Pathology presents histological illustrative material from paraffin and semi-thin sections of the human testis which are routinely used in the assessment of testicular morphology, allowing an early detection of carcinoma in situ and more advanced pathological changes of the testicular parenchyma. The early detection of cancer in situ is based on the careful morphological investigation of the biopsy and immunohistochemistry (IHC). Therefore, this atlas contains detailed descriptions of IHC methods as well as modern molecular biological methods such as DNA microarrays and proteomics and advanced microscopy techniques related to the testicular biopsy. Adequate evaluation of the testicular biopsy leads to high cure rates of testicular neoplasms which can be used as a basis to successfully treat infertility in men. Atlas on the Human Testis: Normal Morphology and Pathology is a valuable reference tool which will appeal to andrologists, urologists, pathologists, clinical embryologists, as well as reproductive biology scientists.
Stem Cells in Reproductive Tissues and Organs
This contributed volume gathers the latest knowledge in the field of stem cells in human reproductive organs, as well as animal models, and to consider the possibility of using this knowledge for clinical purposes. The scope of the book covers both clinical and basic knowledge of stem cells in both reproductive medicine (gynecology and obstetrics) and regenerative medicine as well as cellular and molecular medicine and reproductive biology. Chapters on basic stem cell knowledge in human reproductive tissues and organs or animal models are included, as well as clinical knowledge on their role in the manifestation of infertility and cancer and their clinical use.
Liquid Biopsy
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Entwicklungsbezogene und altersabhängige Besonderheiten im Hoden und Nebenhoden
Die vorliegende Doktorarbeit beschäftigt sich mit entwicklungsbezogenen und altersabhängigen Besonderheiten im Hoden und Nebenhoden. Der erste Abschnitt „Entwicklungsbezogene Vorgänge im Nebenhoden“ umfasst die Untersuchung der glatten Muskelzellen des Nebenhodenganges während der prä- und neonatalen Entwicklung. Im Nebenhodengang, der Hauptstruktur des Nebenhodens, reifen die noch unbeweglichen Spermatozoen während ihres Muskelzellabhängigen Transportes durch den Gang, bevor sie im distalen Abschnitt gespeichert werden. Funktion, Regulation und Relevanz der Kontraktionen des Nebenhodenganges vor der Pubertät sind noch unklar. Ziel dieses Abschnittes war es, die Kontraktionen zu ...
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