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Basic Mechanisms and Clinical Treatment of Tumor Metastasis provides information pertinent to the basic mechanism of tumor metastasis and the clinical results with immunochemotherapy of cancer. This book explores the extensive studies of clinical trials of cancer immunotherapy by Japanese investigators who played a significant role in the clinical assessment of different immunomodulating drugs. Organized into five parts encompassing 36 chapters, this book begins with an overview of both the in vivo and in vitro behavior of metastatic tumor cells. This text then examines the pathogenesis of cancer metastasis and its possible modulation by immune cells per se of by those treated with immunopotentiators in experimental animals. Other chapters consider the effects of different soluble immune mediators on tumor cell growth and metastasis. This book discusses as well the immunobiology and immunopathology of human tumor cell metastasis. The final chapter deals with successful and unsuccessful trials with cancer immunotherapy using various biological and chemical compounds. This book is a valuable resource for biologists, oncologists, and clinical researchers.
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This comprehensive Handbook is the first to provide a practical, interdisciplinary review of ethical issues as they relate to quantitative methodology including how to present evidence for reliability and validity, what comprises an adequate tested population, and what constitutes scientific knowledge for eliminating biases. The book uses an ethical framework that emphasizes the human cost of quantitative decision making to help researchers understand the specific implications of their choices. The order of the Handbook chapters parallels the chronology of the research process: determining the research design and data collection; data analysis; and communicating findings. Each chapter: Explo...
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Seeking reason in the impassioned globalization debate, de laDehesa examines who stands to win and who stands to lose from theprocess of globalization, in a style accessible to readersunfamiliar with economic theory. Objectively and dispassionately illuminates the emotionallycharged globalization debate; Acknowledges that the costs and benefits of globalization willnot be distributed evenly; Details the economic effects of globalization on individuals,governments, nation-states and business; Assesses the impact of globalization on both labor markets andfinancial markets, on global economic growth and on incomedistribution and real convergence between different nationaleconomies.
Country-Risk Analysis is a comprehensive, practical guide to the management of international risk and cross-border lending. The last fifteen years of international commercial bank lending have witnessed a classical boom-and-bust cycle. Yet it is only recently that a formalized approach to country risk assessment has been implemented in the major international banks. Ron Solberg's volume provides a state-of-the-art review of the country risk techniques that have evolved in the context of dramatic changes in developing countries' debt service capacity and in international lending itself. It deals comprehensively with sovereign credit decision making, portfolio management, lending behaviour and financial innovations.
The food world has a number of options available to make the food industry more diverse, competitive, and efficient. Innovations in Food Processing investigates some of these options, alternative technologies, and strategies for properly addressing new challenges facing the food industry. It also provides specific examples on how these alternatives can be utilized in specific food products. This book presents a comprehensive review of new technologies to preserve foods, especially those based on nonthermal techniques. It covers a wide range of methods, including high pressure, pulsed electric fields, and hurdle technologies. Other chapters include information about the trends in emerging technologies over the past 40 years and predictive models that describe microbial growth. Expert contributors present thorough research results and critical reviews of each covered technology. The innovative approaches presented in Innovations in Food Processing will result in sound alternatives for addressing the ever-increasing demand for quality foods at a reasonable cost.
The contributors to Best Practices in Quantitative Methods envision quantitative methods in the 21st century, identify the best practices, and, where possible, demonstrate the superiority of their recommendations empirically. Editor Jason W. Osborne designed this book with the goal of providing readers with the most effective, evidence-based, modern quantitative methods and quantitative data analysis across the social and behavioral sciences. The text is divided into five main sections covering select best practices in Measurement, Research Design, Basics of Data Analysis, Quantitative Methods, and Advanced Quantitative Methods. Each chapter contains a current and expansive review of the lit...