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Human tissues often support large, complex microbial communities growing as biofilms that can cause a variety of infections. As a result of an increased use of implanted medical devices, the incidence of these biofilm-associated diseases is increasing: the non-shedding surfaces of these devices provide ideal substrata for colonisation by biofilm-forming microbes. The consequences of this mode of growth are far-reaching. As microbes in biofilms exhibit increased tolerance towards antimicrobial agents and decreased susceptibility to host defence systems, biofilm-associated diseases are becoming increasingly difficult to treat. Not surprisingly, therefore, interest in biofilms has increased dramatically. The application of microscopic and molecular techniques has revolutionised our understanding of biofilm structure, composition, organisation, and activities, resulting in important advances in the prevention and treatment of biofilm-related diseases. The purpose of this book, which was first published in 2003, is to bring these advances to the attention of clinicians and medical researchers.
This book provides a systems-based approach to periodontology and offers a scientific roadmap of the interactions which can lead to periodontal disease.
As biofilms exhibit increased tolerance towards anti-microbial agents and decreased susceptibility to host defense systems, biofilm-associated diseases have become difficult to treat. New techniques have revolutionized our understanding of biofilms, resulting in advances in the prevention and treatment of biofilm-related diseases. This book presents these advances to clinicians and medical researchers.
Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in Microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics including Archaea and “Sick Building Syndrome . Impact factor for 2006: 1.96.
Angela Devine has brought up her younger brother, James, since he was just a few months old. When James, now an inarticulate adolescent, is accused of rape, Angela is faced with a nightmare situation.
Just once, Ann Devine would like life to be straightforward. But there’s just too much drama knocking about for that to happen. Ann’s family is proving a handful at the moment. Her mother moves in after having a fall, her sister Ger is off ‘finding herself’ in India leaving Ann to look after her teenage, wide a-woke, niece Freya. Her daughter Jennifer is dealing with a love triangle that involves her mother-in-law-to-be. It’s all far from simple. Now Rory, her youngest, has set his sights on a future as a local TD and it’s all Ann can do not to box him up and post him off to the backend of wherever is furthest away from his local ‘mentor’, politician, and all-round chancer Patsy Duggan. Just to save him from himself. Of course, that’s not even an option because now the post office is closing down. The locals are up in arms, but what do the powers-that-be care about rural Ireland? Without really meaning to be, Ann finds herself in the thick of things – and things are getting dodgier by the minute. She only wanted to save the village, but sometimes even saviours need saving from themselves.
Proceedings of a symposium held by E.R. Squibb & Sons in Rhodes, on Oct. 26, 1984.
Warm, charming and laugh-out-loud funny... Ann Devine, Ready For Her Close-Up is a little ray of sunshine, sure to delight' Irish Independent Meet Ann Devine, a riddle, wrapped up in a fleece, inside a Skoda Octavia. Now that her youngest has flown the nest, Ann finds herself at a loose end. Until, that is, she is put forward for the Kilsudgeon Tidy Towns Committee. Yet all is not neat and tidy in Kilsudgeon. There are strange sightings of people who aren't local driving 4x4s with a yellow reg, a man bun requesting kefir in the restaurant and a quad bike at a funeral. What does this have to do with rumours of a brand new television series to rival Game of Thrones? And what will it all mean f...
As past, current, or future patients, the public should be the health care system's unwavering focus and serve as change agents in its care. Taking this into account, the quality of health care should be judged not only by whether clinical decisions are informed by the best available scientific evidence, but also by whether care is tailored to a patient's individual needs and perspectives. However, too often it is provider preference and convenience, rather than those of the patient, that drive what care is delivered. As part of its Learning Health System series of workshops, the Roundtable on Value & Science-Driven Health Care hosted a workshop to assess the prospects for improving health and lowering costs by advancing patient involvement in the elements of a learning health system.