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Neurostimulation and Neuromodulation in Contemporary Therapeutic Practice
Clinical applications of neurostimulation or neuromodulation are experiencing rapid growth, driven by an evolution in neurotechnologies, the limitations of pharmacotherapy, and an improving understanding of brain physiology. New methods are promising for intractable or marginally tractable cognitive diseases and for adjunct therapies, as they offer greatly improved spatial and temporal resolution, thereby promising greater specificity and quicker recovery from disease. This book includes up-to-date and in-depth studies of many of these therapies, with chapters addressing their use in epilepsy, spasticity, pain, neurodegeneration, and spinal cord dysfunctions, among others, illustrating their versatility and therapeutic promise for cognitive dysfunction.
Redirecting Alzheimer Strategy
It is fair to say that no brain disease occupies more research study today than Alzheimer's disease (AD). Among the many excellent reasons for this circumstance are the bleak prognosis and relentless progression; large cohorts of baby boomers entering an age of greatly increased cognitive risk; and spectacular advances in medical care that have prolonged lifespan. Often unattributed is the success of the research enterprise that has instilled confidence in AD's ultimate defeat. Yet, despite decades of intense research, AD remains poorly understood, an enigma amid a tide of neuroscientific advance. What these inconclusive results apparently call into question is an understanding of cognition that views it from the bottom up - the study of which is eminently suited by the scientific method - and that dispenses with a philosophy of biology concerned with how organismal properties operate, for which cognition is the medium. Culled from AD's new and old research archives, the chapters in this text accordingly lay out an argument for strategically new pathways that wander through cognition's global terrain and that may ultimately offer surer ground for AD treatment.
Neuroethics in Principle and Praxis
With the conclusion of the Decade of the Brain and Decade of the Mind, neuroscience has advanced well beyond single neuron functions, and begun to investigate global properties that emerge from central nervous system operation. Core ethical issues for neural intervention, in consequence, now touch on concerns over how the individual as a whole may be affected. Central to these concerns is the fundamental value of the human being, which lends normative weight to questions, interventions, and practices influencing him or her. Yet, despite wide recognition of the crucial relevance of human value, the derivation of metaethical principles that underwrite this value is by no means uniformly agreed to. Why and how the human being is normatively privileged, accordingly, emerge as core questions that frame issues of ethical praxis. This book tackles this dissonance, and exposes the philosophical foundations that are rooting contemporary divisions in ethical approaches to intervention in the nervous system.
Evolving BCI Therapy
As a strategic response to cognitive and CNS impairments, BCI is a theoretical outgrowth of several generations of endogenous devices for peripheral nerves, which have as a prime goal the direct replacement of lost neural function. In these earlier applications therapeutic intervention has been premised only on the restoration of signal generating capacity where nerve transmission is largely unidirectional and temporally sequenced. It is increasingly apparent, however, that the brain not only employs a very different type of syntax from that of peripheral nerves but also structures the semantic content of motor activity, fundamentally altering the conception of BCI as a therapeutic medium. The book presented here documents this change, proposing a multi-faceted strategy in which BCI therapy can restore the loss of multi-tiered, brain based motor function.
Sleep Medicine and the Evolution of Contemporary Sleep Pharmacotherapy
Sleep is a fundamental physiological feature experienced by all known mammalian, and most non-mammalian, species. Underscoring its importance is the wide array of neural and cellular processes that have evolved to govern when and how it occurs, its duration, sequence of phases, and the influence it exerts on numerous other brain functions. This book takes up the growing prevalence of sleep disorders affecting these processes and the panorama of pharmaceutical tools that have evolved for their medical care. Its wide-ranging discussion promises not only recent updates on their clinical management but a contemporary window into sleep’s cross-cutting relevance for the many neurological dysfunctions now known to associate with sleep disturbances.
Habits and Holiness
"This comprehensive exploration of Thomas Aquinas's theology of habit takes habits in general as a prism for understanding human action and its influences and provides a unique synthesis of Thomistic virtue theory, modern science of habits, and best practices for eliminating bad habits and living good habits"--
Neuroplasticity
This book provides comprehensive and up-to-date insights into emerging research trends on neuroplasticity with current or future treatments for neurodevelopment and neurodegenerative diseases. The authors discuss structural and functional changes associated with cortical remapping, sensory substitution, synaptic and non-synaptic compensatory plasticity due to brain damage, brain training, chronic pain, meditation, music, exercise and related states. Key features include pathogenesis, and existing and new therapies together with a pharmacological and non-pharmacological approach in clinical treatment and management. The authors are established experts that contributed significantly to a better understanding of the etiology of neuroplasticity. This book is recommended to healthcare providers, clinical scientists, students and patients.
In the Sphere of the Personal: New Perspectives in the Philosophy of Persons
The papers in this collection were originally presented at the 13th International Conference on Persons, held at the University of Boston in August 2015. This biennial event, founded by Thomas O. Buford and Charles Conti in 1989, attracts a host of international scholars, both the venerable and the aspiring. It is widely regarded as the premier event for those whose research concerns the philosophical tradition known as ‘personalism’. That tradition is, perhaps, best known today in its American and European manifestations, although there remains a small but fiercely defended stronghold in Britain. Personalism is not an exclusively Western development, however; its roots are also found in...
Neuroethics and Cultural Diversity
There is a growing discussion concerning the relationship between neuroethical reflections and cultural diversity, which is among the most impactful factors in shaping neuroethics, both as a scientific discipline and a social enterprise. The impacts of culture on science and its public perception are particularly relevant to neuroethics, which aims to facilitate the creation of an interface between neuroscience and society at large. Time is ripe for neuroethics to review the influence of the culturally specific contexts from which it originated (i.e. North America and Western Europe) and to also include other cultural perspectives in the discussion. This book illustrates a convergent approach among different cultures in identifying the main issues raised by neuroscience and emerging technologies. This should be taken as a starting point for advancing in the search for shared solutions, which are, if not definitive, at least sufficiently reliable to be translated into democratic deliberative processes.
