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The Music of Life
What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes. But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself. Noble argues that far from genes building organisms, they should be seen as prisoners of the ...
Dance to the Tune of Life
This book formulates a relativistic theory of biology, challenging the common gene-centred view of organisms.
Understanding Living Systems
Life is definitively purposive and creative. Organisms use genes in controlling their destiny and evolution. Genes do not control life.
The Music of Life
What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes.But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself. Noble argues that far from genes building organisms, they should be seen as prisoners of the o...
Forgotten Warriors
The machines of war, and the effects of combat and its aftermath. The reader is also given a sense of how some writers and artists felt about the country and the people of South Vietnam. To date, our perceptions of the Vietnam War have been influenced largely by movies, television and novels. Recognizing this, Dr. Noble enlisted Professor William J. Palmer, a noted authority on the media and their reportage of the war, to provide an essay that allows the reader to.
Captain "Hell Roaring" Mike Healy
One of the Coast Guard’s great heroes and the secret he kept hidden "This is a book of adventure that tells how one man shaped the Alaskan frontier at a crucial time in American history."--Vincent William Patton, Master Chief Petty Officer of the Coast Guard, retired "Diligent research and precise writing reveal the realities of race relations in nineteenth-century America, as well as the dangers, loneliness, and complex relationships of life at sea in that era."--Bernard C. Nalty, author of Strength for the Fight: A History of Black Americans in the Military In the late 1880s, many lives in northern and western maritime Alaska rested in the capable hands of Michael A. Healy (1839-1904), t...
The Selected Papers of Denis Noble CBE FRS
This is a scientific and philosophical autobiography written around a collection of Denis Noble's most significant papers. It traces a remarkable journey from na ve reductionism to a rigorous systems approach to living systems. It is rigorous because Denis Noble was one of the first biologists to construct computer models of cells and organs of the body. His theoretical work is entirely mathematically based, with no room for ambiguity. Far from the denigration of the systems approach as holistic 'hand-waving', his work is now regarded by pharmaceutical companies and regulators as the gold standard of modelling in the development of new medication. Systems Biology is an idea in search of a definition. This book explains why this is true: it is an approach rather than a subject. Denis Noble's work is one of the clearest examples of the systems approach in practice since it reveals the nature of some of the forms of downward causation in multilevel analysis. The story will delight readers who like to see how scientific controversy is resolved, since many of the developments described in each chapter were highly controversial when they occurred.
The Rescue of the Gale Runner
Indicting U.S. Coast Guard small boat rescue policy and those who fail or refuse to change it, Noble (a former member of the Coast Guard) narrates a 1997 rescue operation which resulted in the death of three members of the rescue team. Noble himself was present at the rescue station on the night of the operation. He relies on his own observations and the words of a number of other officers involved in the case, who collectively suggest that overwork and other easily addressable problems led to the fatalities. Annotation copyrighted by Book News, Inc., Portland, OR.
That Others Might Live
From 1878 to 1915 the U.S. Life-Saving Service was a small federal maritime organization that carried out amazing rescues of those in distress close to shore. Working from small stations scattered along the coastlines of the United States and using only oar-powered boats, none longer than 36 feet, crewmembers came to be known as "storm warriors" as they pulled off rescues that almost defied belief. Considered one of the most valorous organizations ever run by the U.S. government, the service carried out thousands of rescues, and many of its men lost their lives in the effort to save others. Yet since its incorporation into the U.S. Coast Guard in 1915, the feats of this life-saving service h...
The Girl Next Door
Set on the Upper East Side of New York City, The Girl Next Door follows the inhabitants of a co-op building as they search for love, happiness, and the real meaning of home. What makes a house a home? For Eve Gallagher, home is miles away in England since she and her husband relocated to an apartment building on New York's Upper East Side. And life isn't coming up roses. What makes a neighbor a friend? Violet has lived in the building for decades, but she's always kept herself apart, until Eve's loneliness touches her heart. What makes a wife a lover? Jason Kramer in apartment 6A is no longer sure he loves his wife, but he's head over heels for Rachel Schulman in 6B.What makes the girl next door the woman of your dreams? Meeting Emily Mikanowski from 3A turns Trip Grayling's world upside down. It's love at first sight, but he needs help from Charlotte, the shy romance novel addict in 2A, if he's going to get his girl. What they all have in common is an address, but it is also a home where their lives and secrets intertwine. Come in and enjoy this bittersweet story of friendship and love.
