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Alcohol Metabolism, Alcohol Intolerance, and Alcoholism
Alcohol abuse, alcohol intolerance, alcohol dependence and other alcohol-related disabilities are some of the most challenging public health problems facing our modern-day society. The purpose of this comprehensive monograph is to review the available knowledge concerning the pharmacogenetic basis of alcohol sensitivity and its physiolgical implications and to synthesize the bulk of existing knowledge regarding metabolic features and biomedical disturbances related to alcoholism. The chapters cover a broad array of disciplines including an overview of historical and epidemiological aspects, biochemistry and molecular genetics of enzymes involved in alcohol metabolism, biochemical and neuropsychopharmacological effects of alcohol. Major emphasis is placed on the role of genetic factors in alcoholism. The experimental details are summarized and a comprehensive bibliography is included.
Alcohol in Health and Disease
This volume, based on presentations from the symposium on the health effects of alcohol held in Titisee, Germany, examines the physical and psychological consequences of alcohol use and abuse, and considers environmental and ethnic factors that lead to addiction and dependence. Discusses epidemiological studies that show the influence of light to moderate intake of alcoholic beverages on coronary heart disease. Featuring contributions from nearly 60 internationally recognized and respected authors, and over 2900 references for further investigation of the subject, Alcohol in Health and Disease analyzes biochemical, pharmacogenetic, and pathologic disturbances that follow acute and chronic in...
Enzymology and Molecular Biology of Carbonyl Metabolism 5
Since the inception of these meetings in 1982, they have always been a satellite of the International Society for Biomedical Research on Alcoholism meeting. At our 1992 meeting in Dublin we learned that the next ISBRA meeting would be held in Brisbane, of all our previous meetings, I was very concerned Australia. As the scientific organizer about holding a meeting in the Southern Hemisphere for fear that many of our potential participants would not travel that far. I am pleased to say that I was proven to be incorrect. Nearly 90 scientists from a dozen countries participated at our seventh conference. At this meeting, like at all our previous ones, much new information about the three enzyme...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Alcohol and Aldehyde Metabolizing Systems-IV
The papers in this book represent the proceedings of the Third International Symposium, which was held at the Addiction Research Foundation in Toronto in July, 1979. The purpose of this meeting was to bring together experts in the field from a wide variety of backgrounds in an attempt to gain some clarity and insight into the problems of alcohol and aldehyde metabolism. One might ask, "Why have such a meeting and a collection of research papers?" The answer is clear. The societal problem of alcoholism is, unlike many other health problems, growing instead of abating. Treatment efforts are largely ineffective (e.g., Griffith Edwards' classic work)', and fundamental research has yet to identif...
The Genetic Basis of Common Diseases
Since the first edition of this highly acclaimed text was published in 1992, much new knowledge has been gained about the role of genetic factors in common adult diseases, and we now have a better understanding of the molecular processes involved in genetic susceptibility and diseases mechanisms. The second edition fully incorporates these advances. The entire book has been updated and twelve new chapters have been added. Most of these chapters deal with diseases such as gallstones, osteoporosis, osteoarthritis, skin cancer, other common skin diseases, prostate cancer and migraine headaches that are seen by all physicians. Others address the genetic and molecular basis of spondylarthropathies, lupus, hemochromatosis, IgA deficiency, mental retardation, hearing loss, and the role of mitochondrial variation in adult diseases. Chapters on the evolution of human genetic disease and on animal models add important background on the omplexities of these diseases. Unique clinical applications of genetics to common diseases are covered in the additional new chapters on genetic counseling, pharmacogenetics, and the genetic consequences of modern therapeutics.
Enzymology and Molecular Biology of Carbonyl Metabolism 3
The Fifth International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism was held at Purdue University in June, 1990. This represents the fifth time that I had the privilege of organizing the scientific program. It was the first time that I actually hosted the meeting. I wish to salute my four previous co-organizers and the thousands of scientists who have hosted other meetings. It is much easier to arrange the scientific program and edit the proceedings. No local organization could occur without the help of ones research group and, in this case, my wife. I sincerely thank Esther and my research group for their advise and help. At this Workshop, similar to the preceeding ones, much new information was presented. It was apparent how molecular biological techniques were influencing the direction of the research on the three families of enzymes discussed. It also was apparent that not all biochemical problems could be solved by using these techniques. Many of the presentations showed how important advances still could be made using more traditional biochemical approaches.
Alcohol Misuse
This book is based on a series of reports on the health and social consequences of alcohol misuse presented to the European Economic Community. Each of the chapters is written by internationally acclaimed experts, who have reviewed their own chosen fields and contributed possible future research directions. A review of trends in consumption are followed by a report of the racial, ethnic and gender differences in alcohol misuse. The importance of alcohol, as a nutritional source, in the pathogenesis of tissue damage, the role of malnutrition deficiencies in alcohol misusers is also discussed. Chapters review organs which are damaged by misuse, such as the liver, pancreas, brain, muscle, skin, and bone. The relationship between alcohol misuse and malignancy and the HIV disease completes the biomedical areas.
Alcohol Consumption and Alcoholism in Hungary
This volume grew out of a German-Hungarian collaborative research programme on alcohol and alcoholism carried out during the years 1990-93. One of the major objectives of this joint study was to explore the epidemiological and biomedical aspects of alcohol drinking and abuse in Hungary. There are indeed very few systematic surveys available in Hungary concerning these issues. The book covers a number of multidisciplinary topics such as epidemiology, biochemistry, pathophysiology, psychiatry, genetics, teratology, as well as environmental, socio-cultural and ethnic aspects of alcohol use and abuse in Hungary. The authors themselves have, in the past, contributed significantly to alcohol and alcoholism research as well as to population genetic aspects of the Hungarian population. This volume will prove particularly useful to basic scientists and physicians in the area of alcoholism research such as clinicians, geneticists, pharmacologists, toxicologists, psychiatrists, biochemists, environmental and public health scientists, and health policy makers.
