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Biological Potential and Medical Use of Secondary Metabolites
Many macro and micro species, from terrestrial and aquatic environments, produce structurally unique compounds and, in many countries, still are the primary sources of medicines. In fact, secondary metabolites are an important source of chemotherapeutic agents but are also lead compounds for synthetic modification and the optimization of biological activity. Therefore, the exploitation of secondary metabolites, or their inspired synthetic compounds, offers excellent opportunities for the pharmaceutical industry. This Medicines Special Issue focuses on the great potential of secondary metabolites for therapeutic application. The Special Issue contains 16 articles reporting relevant experimental results, and an overview of bioactive secondary metabolites, their biological effects, and new methodologies that improve and accelerate the process of obtained lead compounds with regard to new drug development. We would like to thank all 83 authors, from all over the world, for their valuable contributions to this Special Issue.
Anticancer Plants: Clinical Trials and Nanotechnology
Cancer is one of the leading causes of death in human beings. Though several synthetic medicines are used to treat cancer, they are largely inefficient and unsafe. In contrast, plants, which have been used for medicinal purposes since time immemorial, have proved to be useful in fighting cancer, with natural compounds from plants and their derivatives offering safe and effective treatment and management for several types of cancer. Plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven t...
Seaweeds Secondary Metabolites
Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.
Ordinary People
Shortlisted for the Women's Prize for Fiction, the Orwell Prize for Political Fiction, and the Rathbones Folio Prize Winner of the South Bank Sky Arts Award for Literature A Washington Post "Lily Lit" Book Club Selection
Cancer Care Support 1st International Edition 2022
This compendium is intended to be the first updated review of most of the clinical situations that cancer patients may present. It identifies the clinical picture and the therapeutic orientation, with the degrees of recommendation and evidence, as well as the direct bibliographic reference for each statement. We took a multidisciplinary approach, with the collaboration of 261 authors from 9 countries, 45 hospitals and 19 medical and non-medical specialties. This compendium (IOC 2022) is the result of the effort and innovative spirit of its authors, will be updated every two years. The first international edition of cancer care support based on real world evidence (RWE) contains all the latest news in cancer care support treatment and assigns levels of evidence and grades of recommendation so that the reader can obtain a quick impression and certainty of each of the treatments and strategies presented. The GRADE and OXFORD scales have been used for the levels of evidence.
Advances in Multilingual and Multimodal Information Retrieval
The eighth campaign of the Cross Language Evaluation Forum (CLEF) for - ropean languages was held from January to September 2007. There were seven distinct evaluation tracks in CLEF 2007, designed to test the performance of a wide range of multilingual information access systems or system components. CLEF is by now an established international evaluation initiative and, in 2007, 81 groups from all over the world submitted results for one or more of the di?erent evaluation tracks. Full details regarding the design of the tracks, the methodologies used for evaluation, and the results obtained by the participants can be found in the di?erent sections of these proceedings. As always the results of the campaign were reported and discussed at the annual workshop, held in Budapest, Hungary, 19-21 September, immediately following the eleventh European Conference on Digital Libraries. The workshop playsanimportantrolebyprovidingtheopportunityforallthe groupsthathave participated in the evaluation campaign to get together to compare approaches and exchange ideas.
Handbook of Research on Strategic Innovation Management for Improved Competitive Advantage
Innovation is a vital process for any business to remain competitive in this age. This progress must be coherently and optimally managed, allowing for successful improvement and future growth. The Handbook of Research on Strategic Innovation Management for Improved Competitive Advantage provides emerging research on the use of information and knowledge to promote development in various business agencies. While covering topics such as design thinking, financial analysis, and policy planning, this publication explores the wide and complex relationships that constitute strategic innovation management principals and processes. This publication is an important resource for students, professors, researchers, managers, and entrepreneurs seeking current research on the methods and tools regarding information and knowledge management for business advancement.
Re-imagining the Teaching of European History
This book explores the challenges of teaching European history in the 21st century and provides research-informed approaches to history teaching that combine civic education, historical consciousness, and the teaching of controversial social issues. With contributions from researchers across Europe, the book includes both theoretical and case study chapters. The first part of the book addresses issues such as globalization and teaching in an interconnected world, using multicultural and critical approaches, decolonizing education, and teaching uncomfortable narratives of the past. The second part of the book showcases thematic chapters dedicated to teaching intersecting topics in the Europea...
Global Gifts
Global Gifts considers the role that the circulation of material culture played in the establishment of early modern global diplomacy.
Evaluating Systems for Multilingual and Multimodal Information Access
The ninth campaign of the Cross-Language Evaluation Forum (CLEF) for European languages was held from January to September 2008. There were seven main eval- tion tracks in CLEF 2008 plus two pilot tasks. The aim, as usual, was to test the p- formance of a wide range of multilingual information access (MLIA) systems or s- tem components. This year, 100 groups, mainly but not only from academia, parti- pated in the campaign. Most of the groups were from Europe but there was also a good contingent from North America and Asia plus a few participants from South America and Africa. Full details regarding the design of the tracks, the methodologies used for evaluation, and the results obtained by t...
