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Because stroke is essentially a disease of the vessels and blood flow, the most fundamental aspects of ischemic blood flow in the brain are under investigation by researchers. Their work was the focus of the sixth in the series of Keio University International Symposia for Life Sciences and Medicine, held in Tokyo in 1999. Selected here are 55 papers from the symposium, covering the buffy coat (glycocalyx) of endothelial cells, the blood-brain barrier and permeability, gene expression, vascular reactivity, dysregulation, inflammatory deterioration, cortical spreading depression, edema, microvascular derangement, and pathology, in ten major sections. The book includes the thought-provoking discussions that followed the presentations, thus providing an invaluable source of up-to-date information not only for researchers investigating microcirculation but also for clinicians implementing the most effective treatment for stroke patients.
The idea of this book originated from two series of lectures given by us at the Physics Department of the Catholic University of Petr6polis, in Brazil. Its aim is to present an introduction to the "algebraic" method in the perturbative renormalization of relativistic quantum field theory. Although this approach goes back to the pioneering works of Symanzik in the early 1970s and was systematized by Becchi, Rouet and Stora as early as 1972-1974, its full value has not yet been widely appreciated by the practitioners of quantum field theory. Becchi, Rouet and Stora have, however, shown it to be a powerful tool for proving the renormalizability of theories with (broken) symmetries and of gauge ...
Operational Quantum Physics offers a systematic presentation of quantum mechanics which makes exhaustive use of the full probabilistic structure of this theory. Accordingly the notion of an observable as a positive operator valued (POV) measure is explained in great detail, and the ensuing quantum measurement theory is developed and applied both to a resolution of long-standing conceptual and interpretational puzzles in the foundations of quantum mechanics, and to an analysis of various recent fundamental experiments. The book, or different parts of it, may be of interest to advanced students or researchers in quantum physics, to philosophers of physics, and to mathematicians working in operator valued measures.
The investigation ofmost problems of quantum physics leads to the solution of the Schrodinger equation with an appropriate interaction Hamiltonian or potential. However, the exact solutions are known for rather a restricted set of potentials, so that the standard eternal problem that faces us is to find the best effective approximation to the exact solution of the Schrodinger equation under consideration. In the most general form, this problem can be formulated as follows. Let a total Hamiltonian H describing a relativistic (quantum field theory) or a nonrelativistic (quantum mechanics) system be given. Our problem is to solve the Schrodinger equation Hlft = Enlftn, n i. e. , to find the ene...
Providing a cutting-edge profile of research progress in this important field of study, Cholinergic Mechanisms: Function and Dysfunction contains a compilation of the proceedings of the Eleventh ISCM, held in St. Moritz, May 2002. Bringing together 250 contributors from 30 countries, the book presents a comprehensive picture of the cholinergic field. It provides a survey of current understanding of molecular, pharmacological, toxicological, behavioral, and clinical aspects of the cholinergic system. This volume offers a state-of-the-art account of progress in the field from the molecule in the test tube through the cell and the synapse, to the organism and the patient.
This valuable reference provides a wide range of practical, clinical information for physicians who care for patients with neurological and cardiac problems. Clinical Neurocardiology considers neurological complications arising from cardiac surgery and other cardiac interventions describes neurological findings in heart dise
In this monograph the recursion method is presented as a method for the analysis of dynamical properties of quantum and classical many-body systems in thermal equilibrium. Such properties are probed by many different experimental techniques used in materials science. Several representations and formulations of the recursion method are described in detail and documented with numerous examples, ranging from elementary illustrations for tutorial purposes to realistic models of interest in current research in the areas of spin dynamics and low-dimensional magnetism. The performance of the recursion method is calibrated by exact results in a number of benchmark tests and compared with the performance of other calculational techniques. The book addresses graduate students and researchers.
This book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, β-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. A wide range of systems not addressed in the first edition are covered, reflecting the advances made in recent years. The book combines the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all with an interest in clinical and preclinical neuroscience. Companion volumes on the use of PET and SPECT in neurology and psychiatry complete a trilogy.
This comprehensive reference on therapeutic repetitive transcranial magnetic stimulation (rTMS) documents the current status in the field. The main focus is the clinical applications of rTMS tested to date, including treatment of paresis, aphasia, and visual neglect in stroke patients, therapy for motor impairment in Parkinson’s disease, and applications for tinnitus and neuropathic pain. Based on the available clinical evidence (RCTs, meta-analyses, and systematic reviews), combined with the personal experience of experts, a clinically oriented best evidence synthesis is provided for each application, together with a clear description of rTMS algorithms that generate clinical benefits in the target domain. A further feature is the presentation of a theoretical model of therapeutic action for each therapeutic target. The book will be invaluable for clinicians and researchers in neurology and related fields, including neurologists, physiatrists, as well as ENT and pain specialists.
Since it may seem strange for a new series to begin with volume 3, a word of explanation is in order. The series, Philosophy and Technology, inaugurated in this form with this volume, is the official publication of the Society for Philosophy & Technology. Approximately one volume each year is tobe published, alternating between proceedings volumes - taken from contributions to biennial international conferences of the Society - and miscellaneous volumes, with roughly the character of a professional society journal. The forerunners of the series in its present form were two proceedings volumes: Philosophy and Technology (1983), edited by Paul T. Durbin and Friedrich Rapp, and Philosophy and T...