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The eye is often times referred to as the ”window to the soul”. This is relevant to the practice of medicine as many systemic disorders can present with eye manifestations that can be detected by routine ophthalmic examination and the findings used to help physicians in the diagnosis and management of an individual patient. Conditions with potential eye manifestations include infections, metabolic disorders, auto-immune diseases, and exposure, to name a few. With respect to the latter, various toxicological exposures, whether environmental or clinical, can manifest with eye findings. Some associations are well characterized, such as crystalline retinal deposits that can occur with prolonged tamoxifen use, while others are less well described or understood.
Design and Development of New Nanocarriers focuses on the design and development of new nanocarriers used in pharmaceutical applications that have emerged in recent years. In particular, the pharmaceutical uses of microfluidic techniques, supramolecular design of nanocapsules, smart hydrogels, polymeric micelles, exosomes and metal nanoparticles are discussed in detail. Written by a diverse group of international researchers, this book is a valuable reference resource for those working in both biomaterials science and the pharmaceutical industry. - Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products - Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years - Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry
This book describes the state of the art and future prospects of the most important bio-medicolegal subdisciplines in the post-genomic framework of personalized medicine. Focusing on the three main themes Innovation, Unitariness and Evidence, the book addresses a wide range of topics, including: Bio-Medicolegal and Criminological Sciences, Forensic Pathology and Anthropology, Clinical and Forensic Medicine in Living Persons (from Interpersonal Violence to Personal Injury and Damage, Malpractice, Personal Identification and Age Estimation), Forensic Genetics and Genomics, and Toxicology and Imaging. The unitariness of the “Bio-Medicolegal Sciences”, historically founded on the accuracy and rigor of the methods of ascertainment and criteria of evaluation, should be re-established on the basis of molecular evidence, and used to promote Personalized Justice. Taken together, the book’s conclusions and future perspectives outline a vision of transdisciplinary innovation and future evidence in the framework of personalized justice.
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During recent decades, there has been a steady increase in the use of chemical pesticides in both developed and developing countries. This has caused widespread concern about their impact on human health and on the environment. This is particularly the case in less developed countries which may lack appropriate resources to minimize the risks and rectify problems. The purpose of this book is to provide a review of:information on the scale of manufacture, import, export and use of chemical pesticides; examples of direct risks to human welfare in terms of acute poisonings caused by occupational exposure and pesticide residues in food; examples of problems with the storage of obsolete stocks of pesticides in developing countries. The focus is on acute problems in developing countries, particularly in Latin America, Asia and Africa, but some information is also provided about developed countries.
Lev Tolstoy Dünyayı Yazan Dev Yazar • Lars Iyer: “Edebiyatın bir görevi de hafiflik.” • William Huben: Mahşerin Dört Atlısı: Kierkegaard, Dostoyevski, Nietzsche ve Kafka • Mark Twain: Hikâye Nasıl Anlatılır? • John Fowles: Okumanın Hazzı Edebiyatımızın önde gelen dergilerinden Notos, yaptığı bütün yazar dosyalarını kalıcı bir kaynağa dönüştüren anlayışıyla bu sayıda Lev Nikolayeviç Tolstoy’a yöneliyor. Tolstoy dünya edebiyatında adından en çok söz edilen yazarlardan. Her dönemde yeniden okunmayı gerektiriyor. Semih Gümüş sunuş yazısında, “Tolstoy’u uzaktan okuyamazsınız. Sesini nasıl duyacaksınız. Yakından okumaya ba...
Gerek antik çağ medeniyetlerinin Anadolu'da gelişmesi gerekse Hıristiyanlığın ilk dönemlerinde havarilerin ve Hz. İsa’ya inananların Anadolu’yu güvenli topraklar olarak görmesi; yeniçağda ise Yahudilerin bulundukları yerlerde karşılaştıkları baskıcı/yok edici yaklaşımlardan kaçarak Anadolu topraklarına sığınmış olmaları ve yine Türklerin kendi dinlerine ait eserleri yapmaları, üzerinde yaşadığımız bu toprakların farklı bölgelerinde kiliselerin, sinagogların ve camilerin inşa edilmesine neden olmuştur. Anadolu toprakları, sadece somut kültürel mirasın izlerini taşımakla kalmamış, efsanelere ve fenomenlere de ev sahipliği yapmıştır....