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Plants, Stress & Proteins
Biotic and abiotic stress factors deliver a huge impact on plant life. Biotic stress factors such as damage through pathogens or herbivore attack, as well as abiotic stress factors like variation in temperature, rainfall and salinity, have placed the plant kingdom under constant challenges for survival. As a consequence, global agricultural and horticultural productivity has been disturbed to a large extent. Being sessile in nature, plants cannot escape from the stress, and instead adapt changes within their system to overcome the adverse conditions. These changes include physiological, developmental and biochemical alterations within the plant body which influences the genome, proteome and ...
Natural Products and Nano-Formulations in Cancer Chemoprevention
This book covers various aspects of cancer chemoprevention, including an overview of chemoprevention in the process of tumorigenesis; the roles of various phytochemicals, functional foods, and dietary interventions in disease prevention; and techniques such as cancer stem cell targeting, nano-formulations, and so forth. The nutrigenomic and epigenetic effects of natural products at the molecular and genetic levels are also covered alongside their potential for additive and synergistic effect, as well as overcoming drug resistance. The key selling features of the book are as follows: Discusses holistic and comprehensive areas of chemoprevention Includes diverse techniques, such as cancer stem...
Root systems biology
The understanding of biological complexity has been greatly facilitated by cross-disciplinary, holistic approaches that allow insights into the function and regulation of biological processes that cannot be captured by dissecting them into their individual components. In addition, the development of novel tools has dramatically increased our ability to interrogate information at the nucleic acid, protein and metabolite level. The integration and interpretation of disparate data sets, however, still remain a major challenge in systems biology. Roots provide an excellent model for studying physiological, developmental, and metabolic processes. The availability of genetic resources, along with ...
International Plant Proteomics Organization (INPPO) World Congress 2014
The field of proteomics has advanced considerably over the past two decades. The ability to delve deeper into an organism’s proteome, identify an array of post-translational modifications and profile differentially abundant proteins has greatly expanded the utilization of proteomics. Improvements to instrumentation in conjunction with the development of these reproducible workflows have driven the adoption and application of this technology by a wider research community. However, the full potential of proteomics is far from being fully exploited in plant biology and its translational application needs to be further developed. In 2011, a group of plant proteomic researchers established the ...
Targeting Cellular Signalling Pathways in Lung Diseases
The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
Recent Advances in Nanocarriers for Pancreatic Cancer Therapy
Recent Advances in Nanocarriers for Pancreatic Cancer Therapy reviews thriving strategies concerning pancreatic cancer therapy, thoroughly describing the most recent developments in emerging modern drug delivery systems focused on, and derived from, nanotechnology. By providing a holistic understanding of the molecular pathways, conventional therapy and novel nanocarriers mediated drug delivery against pancreatic cancer, this work can be considered a complete package. The book offers a solution to the dissemination of data from a broad range of resources by providing an overview of the molecular pathways and conventional therapy of pancreatic cancer, the application of various nanocarriers, ...
Carbon Nanostructures in Biomedical Applications
This book provides a holistic compilation on applications of carbon nanostructures, especially in advanced healthcare applications. It comprises chapters on utility of diverse multifunctional nanocarriers in drug delivery and biomedical applications, especially emphasizing on the synthesis and characterizations of nanosystems along with surface engineering approaches used for active targeting of the drugs. Moreover, the chapters also include the recent updates on the applications of the nanocarriers to fulfill the needs of various healthcare systems.
Plants; Stress & Proteins
Biotic and abiotic stress factors deliver a huge impact on plant life. Biotic stress factors such as damage through pathogens or herbivore attack, as well as abiotic stress factors like variation in temperature, rainfall and salinity, have placed the plant kingdom under constant challenges for survival. As a consequence, global agricultural and horticultural productivity has been disturbed to a large extent. Being sessile in nature, plants cannot escape from the stress, and instead adapt changes within their system to overcome the adverse conditions. These changes include physiological, developmental and biochemical alterations within the plant body which influences the genome, proteome and ...
Advances in CRISPR/Cas and Related Technologies
Advances in CRISPR/Cas and related technologies, Volume 179, the latest release in this ongoing series, deals with a wide variety of research topics related to recent advancement in the genome editing techniques. Associated chapters in this new release include Challenges for Therapeutic application of CRISPR Cas techniques, Mitochondrial DNA modification by CRISPR Cas System: Challenges and future direction, Trends in CRISPR Cas technology application in cancer, Modified CRISPR-Cas for next generation application, Application of CRISPR Cas in Synthetic Biology: Challenges and Scopes, History of CRISPR Cas system from bacterial Adaptive Immune System to research application, and more. Covers the Cas9 protein modification for reduced off-target effect Includes discussions on Cas9 utilization for Metabolic Engineering Provides information on the use of Cas9 for targeted delivery in therapeutic application
Nanomaterials for Drug Delivery and Therapy
Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. Assesses the opportunities and challenges of nanotechnology-based drug delivery systems Explores how nanotechnology is being used to create more efficient drug delivery systems Discusses which nanomaterials make the best drug carriers
