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Celebrating its one-hundredth anniversary in February 2009, the National Association for the Advancement of Colored People (NAACP) has been the leading and best-known African American civil rights organization in the United States. It has played a major, and at times decisive, role in most of the important developments in the twentieth century civil rights struggle. Drawing on original and previously unpublished scholarship from leading researchers in the United States, Britain, and Europe, this important collection of sixteen original essays offers new and invaluable insights into the work and achievements of the association. The first part of the book offers challenging reappraisals of two...
The last two years have witnessed a continuation in the breakthrough shift toward pulse tube cryocoolers for long-life, high-reliability cryocooler applications. New this year are papers de scribing the development of very large pulse tube cryocoolers to provide up to 1500 watts of cooling for industrial applications such as cooling the superconducting magnets of Mag-lev trains, coolmg superconducting cables for the power mdustry, and liquefymg natural gas. Pulse tube coolers can be driven by several competing compressor technologies. One class of pulse tube coolers is referred to as "Stirling type" because they are based on the linear Oxford Stirling-cooler type compressor; these generally ...
In three Volumes this mini book series presents current knowledge and new perspectives on cartilage as a specialized yet versatile tissue. This first volume provides a comprehensive overview on the basic composition and development of cartilaginous tissues followed by the description of the major signaling pathways which regulate cartilage morphogenesis and function. This book addresses Professors, researchers and PhD students who are interested in musculoskeletal and cartilage biology.
Interest in the factors controlling the spread of pathogenic bacteria in both human and animal populations has led, in recent years, to the development of various techniques for the characterization of isolates from epidemics. These take many forms. Biochemical tests, serological analysis, phage and bacteriocin typing are particularly important. Volumes 10-13 of Methods in Microbiology collect together, for the first time, the methods used in identifying all major human and animal pathogenic bacteria of epidemiological importance. The attention to practical detail will enable the methods to be followed in the laboratory, and it is hoped that this will lead to increased uniformity of methods around the world.These volumes will be of value to workers in epidemiology, clinicians working in infectious disease clinics, microbiologists concerned with environmental health and general microbiologists wanting an insight into current thinking and practice concerning the identification of bacteria at the species and sub-species level.
CS is an unbranched, polydisperse, complex glycosaminoglycan extracted and purified from various tissues. This polyanion is interacting with both plasma and cells, it is able to modulate many biochemical and physiologic processes. Due to the presence of sulfate groups in different amounts and located in various positions, CS represents a very heterogeneous family of polysaccharides. therefore, the preparative approach and the analytical techniques are of paramount importance to produce CS with specific structure and properties and of pharmaceutical grade.*Includes recent technologies and methodologies to study and understand the structure and properties of chondroitin sulfate (CS)*Authoritative contributors from the scientific community with expertise in the field of CS and complex polysaccharides*Detailed and accurate figures to describe and illustrate complex molecular and macromolecular structures and properties
Looking at the area of the extracellular matrix of connective tissue, including the results and concepts which have recently been generated, this text describes the structural characteristics of extracellular molecules and discusses the interaction between the cell and the extracellular matrix.
This book provides a comprehensive, up-to-date review of the structure, biology, and molecular interactions of proteoglycans, consolidating into a single source research using molecular, cellular, and animal systems. Of particular note is an in-depth look at the role of heparan sulfate in modulating growth factors and morphogens.
Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and perhaps safer antiplatelet drugs is one of the most active areas of investigation in both basic and cli...